N'-(chloro(4-fluorophenyl)methylene)-4-fluorobenzohydrazonoyl chloride | 36342-48-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N'-(chloro(4-fluorophenyl)methylene)-4-fluorobenzohydrazonoyl chloride
• 英文别名: 1,2-bis[(4-fluorophenyl)chloromethylidene]hydrazine；1,2-bis(chloro(4-fluorophenyl)methylene)hydrazine；N-[chloro-(4-fluorophenyl)methylidene]-4-fluorobenzenecarbohydrazonoyl chloride
• CAS: 36342-48-0
• 化学式: C₁₄H₈Cl₂F₂N₂
• 分子量: 313.134
• InChiKey: WHGNQPBERBSNDU-UHFFFAOYSA-N

物化性质

• 沸点：
  382.7±52.0 °C(Predicted)
• 密度：
  1.33±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N'-(chloro(4-fluorophenyl)methylene)-4-fluorobenzohydrazonoyl chloride 以 二氯甲烷 、 N,N-二甲基苯胺 为溶剂， 反应 54.0h， 生成 tris[3,5-bis(4-fluorophenyl)-4-phenyl-4H-1,2,4-triazolato]iridium(III)
  参考文献：
  名称：

  JP5787538

  摘要：

  公开号：
• 作为产物：
  描述：

  4-氟苯甲酰肼 在 五氯化磷 作用下， 以 N-甲基吡咯烷酮 、 甲苯 为溶剂， 反应 7.0h， 生成 N'-(chloro(4-fluorophenyl)methylene)-4-fluorobenzohydrazonoyl chloride
  参考文献：
  名称：

  JP5787538

  摘要：

  公开号：

文献信息

• 3,6-Substituted-1,2,4,5-tetrazines: tuning reaction rates for staged labeling applications
  作者：Danzhu Wang、Weixuan Chen、Yueqin Zheng、Chaofeng Dai、Ke Wang、Bowen Ke、Binghe Wang

  DOI：10.1039/c4ob00280f

  日期：——

  Cycloaddition reactions involving tetrazines have proven to be powerful bioorthogonal tools for various applications. Conceivably, sequential and selective labeling using tetrazine-based reactions can be achieved by tuning the reaction rate. By varying the substituents on tetrazines, cycloaddition rate variations of over 200 fold have been achieved with the same dienophile. Upon coupling with different dienophiles, such as norbornene, the reaction rate difference can be over 14 000 fold. These substituted tetrazines can be very useful for selective labeling under different conditions.

  涉及四氮杂环的环加成反应已被证明是多种应用的强大生物正交工具。可以想象，通过调整反应速率，可以实现基于四氮杂环的顺序和选择性标记。通过改变四氮杂环上的取代基，已实现与相同的二烯亲和体相比超过200倍的环加成速率变化。与不同的二烯亲和体（如诺尔本烯）耦合时，反应速率差异可超过14,000倍。这些取代的四氮杂环在不同条件下的选择性标记中非常有用。
• Poly(<i>p</i>-phenylenevinylene) Derivatives Containing Electron-Transporting Aromatic Triazole or Oxadiazole Segments
  作者：Shinn-Horng Chen、Yun Chen

  DOI：10.1021/ma048990m

  日期：2005.1.1

  report the synthesis, optical and electrochemical details, and properties of copolymers P1−P3 consisting of alternate hole-transporting 1,4-bis(hexyloxy)-2,5-distyrylbenzene (HDB) and electron-transporting 4-(4-(hexyloxy)phenyl)-3,5-diphenyl- 4H-1,2,4-triazole (EDT) or 2,5-diphenyl-1,3,4-oxadiazole (EDO) segments linked via an ether spacer or a twisted σ-bond (biphenyl). These copolymers are soluble

  我们报告的共聚物的合成中，光学和电化学细节，和属性P1 - P3由备用空穴传输1,4-双（己氧基）-2,5-二苯乙烯基苯（HDB）和电子传输4-（4-（己氧基）苯基）-3,5-二苯基-4 H -1,2,4-三唑（EDT）或2,5-二苯基-1,3,4-恶二唑（EDO）链段通过醚间隔基或扭曲连接σ键（联苯）。这些共聚物可溶于常见的有机溶剂，如氯仿，NMP和1,1,2,2-四氯乙烷，并具有良好的热稳定性，分解温度高于375°C。P1 - P3在光激发时显示出从EDT或EDO到EDO荧光团的有效能量转移。的光学和电化学性质通过与含有相似发色团的P4和P5进行比较，还对P1 - P3进行了详细研究。从循环伏安图的发作氧化和还原电势为分离P1和缀合P2是相当的，这表明在扭曲σ键的效果P2是类似于醚间隔物的P1。P2和P3的优化几何结构表明，基于MNDO半经验计算，HDB与EDT或EDO之间的扭转角分别为83
• A general and efficient entry to asymmetric tetrazines for click chemistry applications
  作者：Danzhu Wang、Weixuan Chen、Yueqin Zheng、Chaofeng Dai、Lifang Wang、Binghe Wang

  DOI：10.1515/hc-2013-0072

  日期：2013.6.1

  The importance of click chemistry is widely recognized. Among all the known click reactions, those involving tetrazines represent the fastest click reactions reported and are generating a great deal of interest. However, there is no efficient entry to asymmetric tetrazines and those with strong electron withdrawing groups, which limits the development of this field. Herein, we report a general and efficient entry to asymmetric tetrazines with strongly electron withdrawing groups.

  标题：摘要 重要性点击化学被广泛认可。在所有已知的点击反应中，涉及四氮唑的反应代表了报道的最快点击反应，并引起了极大的兴趣。然而，目前没有高效的不对称四氮唑和带有强电子吸引基团的四氮唑的方法，这限制了该领域的发展。在这里，我们报告了一种通用且高效的方法，用于制备带有强电子吸引基团的不对称四氮唑。
• Bipolar copoly(aryl ether) containing distyrylbenzene, triphenylamine, and 1,2,4-triazole moieties: Synthesis and optoelectronic properties
  作者：Chia-Shing Wu、Shawn-Lin Lee、Yun Chen

  DOI：10.1002/pola.24747

  日期：2011.7.15

  A novel copoly(aryl ether) (P1) consisting of alternate emitting segments (distyrylbenzene) and a bipolar moiety composed of directly linked electron‐transporting aromatic 1,2,4‐triazole and hole‐transporting triphenylamine was synthesized. The copoly(aryl ether) is readily soluble in common organic solvents and exhibit good thermal stability with thermal decomposition temperature above 450 °C. The

  合成了一种新型的由交替发射链段（二苯乙烯基苯）和由直接连接的电子传输的芳香族1,2,4-三唑和空穴传输的三苯胺组成的双极性部分组成的共聚（芳基醚）（P1）。共聚（芳基醚）易溶于常见的有机溶剂，并在450℃以上的热分解温度下具有良好的热稳定性。共聚物的发射和光致发光量子产率主要由具有更长发射波长的发射链段（二苯乙烯基苯）决定。引入分离的双极单元后，P1的电子亲和力明显增强，这一点可以通过相对于P0降低的最低未占据分子轨道能级（–2.77 eV）来证实没有双极性单位（–2.34 eV）。由于电荷注入和传输更加平衡，聚合物发光二极管（铟锡氧化物/聚（3,4-乙撑二氧噻吩）：聚（苯乙烯磺酸盐）/ P1 / LiF / Ca / Al）的发射效率得以提高。 。将P1与聚（9,9-二己基芴）（PF）掺混可进一步提高设备的效率。对于PF / P1 = 20 / 0.8（w / w），可获得最佳性能，最大亮度和最大亮度效率分别从380
• Chemical linkage functions of poly(ether imide)s on the resistive switching memory effects
  作者：Kun-Li Wang、I-Hao Shih、Sheng-Tung Huang、Hsin-Luen Tsai

  DOI：10.1016/j.orgel.2014.10.050

  日期：2015.1

  A series of aromatic poly(ether imide)s, AZTA-PEIs containing triphenylamine and 1,2, 4-triazole moieties are prepared and characterized. All the polymers with inherent viscosity from 0.58 to 1.1 dL/g show glass transition temperatures in the range of 250-278 degrees C. Resistive switching memory devices are constructed based on the processable poly(ether imide) (AZTA-PEIa). The device can be switched from the initial OFF state to the ON state under either positive or negative electrical sweep at about +/- 3.2 V. The ON state is nonvolatile and can maintain the high conducting state even turning off the electrical power and applying a reverse bias. The device fulfills the requirements of a write-once read-many times memory (WORM) with a high ON/OFF current ratio up to 10(5) and a long retention time in both ON and OFF states. The bistable switching effects of the polymer result from the conformation-coupled charge transfer from electron donors (triazole-substituted triphenylamine moieties) to electron acceptors (phthalimide moieties). By comparing with the memory behaviors of analogue polymers, the functions of ether and imide in the chemical polymer structure on the memory behaviors are discussed. (C) 2014 Elsevier B.V. All rights reserved.