5-Methyl-1-phenylheptan-4-ol | 1341728-47-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-Methyl-1-phenylheptan-4-ol
• CAS: 1341728-47-9
• 化学式: C₁₄H₂₂O
• 分子量: 206.328
• InChiKey: SGXKDRAAUPATNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-Methyl-1-phenylheptan-4-ol 在 pyridinium chlorochromate 作用下， 生成 5-methyl-1-phenylheptan-4-one
  参考文献：
  名称：

  O-Acetyl Oximes as Transformable Directing Groups for Pd-Catalyzed C−H Bond Functionalization

  摘要：

  O-Acetyl oximes serve as effective directing groups for Pd-catalyzed sp(2) and sp(3) C-H functionalization reactions. The C-H functionalization products can be subsequently transformed into ortho- or beta-functionalized ketones, alcohols, amines, and heterocycles.

  DOI：

  10.1021/ol902720d

文献信息

• PROCESS FOR PRODUCING ALCOHOL ANALOGUE
  申请人：Takasago International Corporation

  公开号：EP3199513A1

  公开（公告）日：2017-08-02

  Provided is a process for producing an optically active hydroxyaldehyde or aminohydroxyaldehyde. The process for producing an optically active hydroxyaldehyde or aminohydroxyaldehyde is characterized by reacting an aldehyde or an imine with a boric acid enol ester in the presence of a copper compound and an optically active bidentate phosphine compound.

  本发明提供了一种生产光学活性羟基醛或氨基羟基醛的工艺。生产光学活性羟基醛或氨基羟基醛的工艺的特点是在铜化合物和光学活性双叉膦化合物存在下，使醛或亚胺与硼酸烯醇酯反应。
• <i>O</i>-Acetyl Oximes as Transformable Directing Groups for Pd-Catalyzed C−H Bond Functionalization
  作者：Sharon R. Neufeldt、Melanie S. Sanford

  DOI：10.1021/ol902720d

  日期：2010.2.5

  O-Acetyl oximes serve as effective directing groups for Pd-catalyzed sp(2) and sp(3) C-H functionalization reactions. The C-H functionalization products can be subsequently transformed into ortho- or beta-functionalized ketones, alcohols, amines, and heterocycles.