2-(phenylthio)malonamide | 22805-18-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2-(phenylthio)malonamide
• 英文别名: Phenylmercapto-malondiamid；phenylsulfanyl-malonic acid diamide；Phenylmercapto-malonsaeure-diamid；2-Phenylsulfanylpropanediamide
• CAS: 22805-18-1
• 化学式: C₉H₁₀N₂O₂S
• 分子量: 210.257
• InChiKey: XJHMSEIBQZRZDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  112
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (甲基硫代)醋酸乙酯 在 乙醚 、 氨 、 sodium ethanolate 作用下， 50.0~170.0 ℃ 、6.67 kPa 条件下， 生成 2-(phenylthio)malonamide
  参考文献：
  名称：

  Diethyl Oxalo-phenoxyacetate, Diethyl Oxalo-(S-phenylmercapto)-acetate and Related Compounds

  摘要：

  DOI：

  10.1021/ja01189a004

文献信息

• KI-catalyzed C–S bond formation <i>via</i> an oxidation relay strategy: efficient access to various α-thio-β-dicarbonyl compounds
  作者：Yi Jiang、Jiao-Xia Zou、Long-Tao Huang、Xue Peng、Jie-Dan Deng、Long-Qing Zhu、Yu-Hang Yang、Yi-Yue Feng、Xiao-Yun Zhang、Zhen Wang

  DOI：10.1039/c8ob00080h

  日期：——

  An efficient and practical methodology to obtain α-thio-β-dicarbonyl compounds was presented under alkaline conditions via potassium iodide (KI) catalysis.

  在碱性条件下，通过碘化钾（KI）催化，提出了一种获得α-硫代-β-二羰基化合物的高效实用方法。
• Studies on Antitumor Substances. IX. Chemical Behaviors of Thiosulfonate toward Active Methylene Compound
  作者：SEIGORO HAYASHI、MITSURU FURUKAWA、YOKO FUJINO、HAYASHI MATSUKURA

  DOI：10.1248/cpb.17.419

  日期：——

  The reactivities of phenyl benzenethiosulfonate, o-nitrophenyl benzenethiosulfonate and 1, 2-bis (benzenesulfonylthio) ethane toward several active methylene compounds were examined. Consequently, bis (phenylmercapto) malondiamide obtained by the reaction of phenyl benzenethiosulfonate with malondiamide at room temperature was found to eliminate readily one of carboxamide and phenylmercapto group by warming at the temperature above 35°. On the other hand, bis (phenylmercapto) malonate was similarly eliminated one of phenylmercapto group under the same condition, without elimination of carboxylate group. 1-Benzylmercapto-1-phenylmercaptomalondiamide and 1-ethyl-1-phenylmercaptomalondiamide were eliminated one of carboxamide group, without elimination of any mercapto group. Moreover, 1, 2-bis (benzenesulfonylthio) ethane was allowed to react with malondiamide and acetylacetone to give cyclic compound, ethylenedithiomalondiamide and ethylenedithioacetylacetone, respectively. With comparison of these reactions, the reaction of benzyl benzenesulfonate with cyanoacetamide was carried out to result in the benzylation of cyanoacetamide.

  对苯基苯硫磺酸盐、邻硝基苯基苯硫磺酸盐和1,2-双(苯磺酰硫)乙烷与几种活性亚甲基化合物的反应性进行了研究。因此，在室温下，苯基苯硫磺酸盐与氨基二甲酸反应得到的双(苯基硫代)氨基二甲酸发现可以在高于35°C的温度下迅速消除其中一个氨基和苯基硫代基。另一方面，双(苯基硫代)马来酸在相同条件下也消除了其中一个苯基硫代基，但未消除羧酸根基。1-苯基硫代-1-苯基硫代氨基二甲酸和1-乙基-1-苯基硫代氨基二甲酸则消除了其中一个羧酰胺基，而没有消除任何硫代基。此外，1,2-双(苯硫酰硫)乙烷与氨基二甲酸和乙酰乙酮反应，分别得到环状化合物乙烯二硫亚氨基二甲酸和乙烯二硫乙酰乙酮。通过比较这些反应，还进行了苄基苯磺酸盐与氰乙酸酰胺的反应，结果导致了氰乙酸酰胺的苄基化。
• [EN] NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE<br/>[FR] PIGMENTS ANTI-CORROSION NON TOXIQUES A BASE DE MANGANESE
  申请人：UNIV DAYTON

  公开号：WO2004065305A1

  公开（公告）日：2004-08-05

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well­founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems.
• Diethyl Oxalo-phenoxyacetate, Diethyl Oxalo-(S-phenylmercapto)-acetate and Related Compounds
  作者：Ernest H. Huntress、Robert T. Olsen

  DOI：10.1021/ja01189a004

  日期：1948.9