N-allyl-N-phenyl-hydrazine; hydrochloride | 71056-17-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-allyl-N-phenyl-hydrazine; hydrochloride
• 英文别名: N-Allyl-N-phenyl-hydrazin; Hydrochlorid；(N-prop-2-enylanilino)azanium;chloride
• CAS: 71056-17-2
• 化学式: C₉H₁₂N₂*ClH
• 分子量: 184.669
• InChiKey: AQUSYBILOTXOEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.16
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  30.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二甲基氢胺 、 N-allyl-N-phenyl-hydrazine; hydrochloride 以 丙醇 为溶剂， 反应 4.0h， 以41%的产率得到1,1-dimethyl-2-(N-prop-2-enylanilino)guanidine
  参考文献：
  名称：

  Synthesis and anti-arrhythmic activity of aminoguanidine derivatives

  摘要：

  A series of new aminoguanidine derivatives were synthesized and tested for anti-arrhythmic activity. The compounds selected were investigated on other test models. Finally, compound 13 1-(2,6-dimethylphenyl)-4,4-dimethyl-aminoguanidine-hydrochloride (B-GYKI-38 233) was chosen for detailed study.

  DOI：

  10.1016/0223-5234(93)90133-y
• 作为产物：
  描述：

  tert-butyl 2-allyl-2-phenylhydrazine-1-carboxylate 、 盐酸 以100%的产率得到
  参考文献：
  名称：

  KATRITZKY, ALAN R.;RAO, M. SURESH CHANDER, J. CHEM. SOC. PERKIN TRANS. PT 1,(1989) N2, C. 2297-2303

  摘要：

  DOI：

文献信息

• KATRITZKY, ALAN R.;RAO, M. SURESH CHANDER, J. CHEM. SOC. PERKIN TRANS. PT 1,(1989) N2, C. 2297-2303
  作者：KATRITZKY, ALAN R.、RAO, M. SURESH CHANDER

  DOI：——

  日期：——
• Synthesis and anti-arrhythmic activity of aminoguanidine derivatives
  作者：I Érczi、G Rablóczky、A Varró、G Somogy I、M Kürthy、I Bódy

  DOI：10.1016/0223-5234(93)90133-y

  日期：1993.1

  A series of new aminoguanidine derivatives were synthesized and tested for anti-arrhythmic activity. The compounds selected were investigated on other test models. Finally, compound 13 1-(2,6-dimethylphenyl)-4,4-dimethyl-aminoguanidine-hydrochloride (B-GYKI-38 233) was chosen for detailed study.