6-benzyloxy-1-(4-bromophenyl)cyclohexene | 1269247-00-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-benzyloxy-1-(4-bromophenyl)cyclohexene
• 英文别名: 1-Bromo-4-(6-phenylmethoxycyclohexen-1-yl)benzene
• CAS: 1269247-00-8
• 化学式: C₁₉H₁₉BrO
• 分子量: 343.263
• InChiKey: GPIBSIUCCKBIJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  环己酮 在 iron(III) chloride 、 氧气 、 sodium iodide 、 二丙基二硫 作用下， 以 氯仿 为溶剂， 反应 48.0h， 生成 6-benzyloxy-1-(4-bromophenyl)cyclohexene
  参考文献：
  名称：

  FeCl₃/NaI-Catalyzed Allylic C–H Oxidation of Arylalkenes with a Catalytic Amount of Disulfide under Air

  摘要：

  This paper describes a FeCl3/NaI-catalyzed formal allylic C-H oxidation of arylalkenes using a catalytic amount of disulfide with BnOH and 4-nitroaniline as nucleophiles and air as oxidant to form the corresponding allyl ethers and amines. A possible reaction mechanism has been proposed.

  DOI：

  10.1021/jo201122s

文献信息

• An Acid-Catalyzed Formal Allylic C−H Oxidation of Aryl Cycloalkenes with <i>N</i>-Propylthiosuccinimide
  作者：Deshun Huang、Haining Wang、Huan Guan、Hu Huang、Yian Shi

  DOI：10.1021/ol200261a

  日期：2011.3.18

  A mild acid-catalyzed formal allylic C-H oxidation of aryl cycloalkenes with N-propylthlosuccinimide in the presence of various nucleophiles to generate allylic ethers, esters, and sulfonamides is described. A possible reaction mechanism has been proposed.
• FeCl₃/NaI-Catalyzed Allylic C–H Oxidation of Arylalkenes with a Catalytic Amount of Disulfide under Air
  作者：Deshun Huang、Haining Wang、Fazhen Xue、Yian Shi

  DOI：10.1021/jo201122s

  日期：2011.9.2

  This paper describes a FeCl3/NaI-catalyzed formal allylic C-H oxidation of arylalkenes using a catalytic amount of disulfide with BnOH and 4-nitroaniline as nucleophiles and air as oxidant to form the corresponding allyl ethers and amines. A possible reaction mechanism has been proposed.