Methylcarbamic acid anthracen-9-yl ester | 10369-95-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: Methylcarbamic acid anthracen-9-yl ester
• 英文别名: anthracen-9-yl N-methylcarbamate
• CAS: 10369-95-6
• 化学式: C₁₆H₁₃NO₂
• 分子量: 251.285
• InChiKey: NKLKCGAFZKWWFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  9-羟基蒽 、 异氰酸甲酯 在 吡啶 作用下， 生成 Methylcarbamic acid anthracen-9-yl ester
  参考文献：
  名称：

  Selective carbamoylation with methyl isocyanate

  摘要：

  DOI：

  10.1021/jo01286a074

文献信息

• SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE
  申请人：SCHERING CORPORATION

  公开号：EP1436284A1

  公开（公告）日：2004-07-14
• ANTICANCER PEPTIDES
  申请人：IDP DISCOVERY PHARMA, S.L.

  公开号：US20200157150A1

  公开（公告）日：2020-05-21

  The present invention provides a peptide of formula (I) or a pharmaceutical salt thereof wherein “m”, “n”, “p”, and “q” represent integers and are selected from 0 and 1; and “r” is comprised from 1 to 10; a linker birradical of formula (II), which is connecting an alpha carbon atom of an amino acid located at position “i” in the peptide sequence of formula (I) with an alpha carbon atom of an amino acid located at position “i+4” or “i+7” in the peptide sequence of formula (I); a C-terminal end corresponding to —C(O)R 4 ; and a N-terminal end corresponding to —NHR 5 . Alternatively, the present invention provides a peptide or a pharmaceutical salt thereof which has an amino acid sequence with an identity from 85% to 95% with respect to sequence SEQ ID NO: 9: The peptides of the invention show anticancer activity. (I) (I) —[(Glu) m -(Lys) n -Ala-Ala-Lys-Val-Val-Ile-Leu-Lys- Lys-Ala-Thr-Glu-Tyr-Val-(His) p -(Ser) q ] r -
• [EN] SYNTHESIS OF 4-[(Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'-[2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE<br/>[FR] SYNTHESE DE 4-[(Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'-[2,4-DIMETHYL-1-OXYDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE
  申请人：SCHERING CORP

  公开号：WO2003033490A1

  公开（公告）日：2003-04-24

  In one embodiment, the present invention describes the synthesis of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4'-bipiperidine, and intermediates therefor from easily available starting materials by a simple route.
• [EN] IRON COMPLEXES AND METHODS FOR POLYMERIZATION<br/>[FR] COMPLEXES DU FER ET PROCÉDÉS DE POLYMÉRISATION
  申请人：HARVARD COLLEGE

  公开号：WO2012109343A2

  公开（公告）日：2012-08-16

  Provided are methods of preparing polymers, such as polyisoprene, polybutadiene, polypiperylene, polycyclohexadiene, poly-β-farnesene, or poly-β-myrcene, using iron complexes. Also provided are novel iron complexes, pre-catalysts, intermediates, and ligands useful in the inventive polymerization system.
• [EN] ARYLCOUMARIN SYNTHESIS WITH AZEOTROPIC REMOVAL OF WATER<br/>[FR] SYNTHÈSE D'ARYLCOUMARINE AVEC ÉLIMINATION AZÉOTROPIQUE DE L'EAU
  申请人：[en]CONAGEN INC.

  公开号：WO2022256480A1

  公开（公告）日：2022-12-08

  The present disclosure provides a method of preparing certain 3,4-dihydro-4-aryl coumarin derivatives. Cinnamic acid, or a certain derivative thereof, may react with phenol, or a certain derivative thereof (e.g., resorcinol), with removal of water azeotropically in the presence of a catalyst and an organic solvent to form a certain 3,4-dihydro-4-aryl coumarin derivative. The present disclosure also provides certain novel 3,4-dihydro-4-aryl coumarin derivatives, and compositions, kits, and methods of use thereof.