di-t-butyl (anthracene-2,6-diyl)dicarbamate | 1335230-37-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: di-t-butyl (anthracene-2,6-diyl)dicarbamate
• 英文别名: tert-butyl N-[6-[(2-methylpropan-2-yl)oxycarbonylamino]anthracen-2-yl]carbamate
• CAS: 1335230-37-9
• 化学式: C₂₄H₂₈N₂O₄
• 分子量: 408.497
• InChiKey: HYUMHZVZKNXFPR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  di-t-butyl (anthracene-2,6-diyl)dicarbamate 在 异丙胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 1.0h， 生成 蒽-2，6-二胺
  参考文献：
  名称：

  An optimized method for the synthesis of 2,6-diaminoanthracene

  摘要：

  The reduction of 2,6-diaminoanthraquinone to 2,6-diaminoanthracene was examined under a variety of conditions. Direct reduction using zinc powder gave a mixture of the target product and 9,10-dihydro-2,6-diaminoanthracene under all the conditions examined. Protection of the starting amine, followed by borohydride reduction and deprotection, gave the target product in 14-50% yield. Finally, tin powder was used to reduce the anthraquinone to 2,6-diaminoanthrone in quantitative yield. This compound was further reduced to the target 2,6-diaminoanthracene in 55-65% yield. Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2011.07.106
• 作为产物：
  描述：

  2,6-二氨基蒽醌 在 4-二甲氨基吡啶 、 sodium tetrahydroborate 、 sodium hydroxide 作用下， 以 N,N-二甲基甲酰胺 、 异丙醇 为溶剂， 生成 di-t-butyl (anthracene-2,6-diyl)dicarbamate
  参考文献：
  名称：

  An optimized method for the synthesis of 2,6-diaminoanthracene

  摘要：

  The reduction of 2,6-diaminoanthraquinone to 2,6-diaminoanthracene was examined under a variety of conditions. Direct reduction using zinc powder gave a mixture of the target product and 9,10-dihydro-2,6-diaminoanthracene under all the conditions examined. Protection of the starting amine, followed by borohydride reduction and deprotection, gave the target product in 14-50% yield. Finally, tin powder was used to reduce the anthraquinone to 2,6-diaminoanthrone in quantitative yield. This compound was further reduced to the target 2,6-diaminoanthracene in 55-65% yield. Published by Elsevier Ltd.

  DOI：

  10.1016/j.tetlet.2011.07.106