N'-(2-hydroxybenzoyl)-2,6-dimethoxybenzohydrazide | 330440-86-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N'-(2-hydroxybenzoyl)-2,6-dimethoxybenzohydrazide
• 英文别名: 2,6-dimethoxybenzoylsalicylhydrazide；H3dmbshz
• CAS: 330440-86-3
• 化学式: C₁₆H₁₆N₂O₅
• 分子量: 316.313
• InChiKey: NHBHUPPOSSJZSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  96.9
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N'-(2-hydroxybenzoyl)-2,6-dimethoxybenzohydrazide 在 氯化亚砜 作用下， 反应 6.0h， 以49%的产率得到2-[5-(2,6-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]phenol
  参考文献：
  名称：

  Spectral Luminescent Properties of 2-Aryl-5-(2,6-dimethoxyphenyl)-1H-1,3,4-oxadiazoles

  摘要：

  2-Aryl-5-(2,6-dimethoxyphenyl)-1H-1,3,4-oxadiazoles were synthesized by cyclization reaction of benzoylbenzohydrazides in SOCl2, and their spectral luminescent properties were studied. The oxadiazoles containing phenyl or o-methoxyphenyl substituents in the position 2 were shown to luminesce with a high quantum yield in polar and nonpolar solvents. The replacement of these substituents by 2-hydroxyphenyl group led to oxadiazole intensely emitting only in highly polar aprotic DMSO.

  DOI：

  10.1134/s107036321802024x
• 作为产物：
  描述：

  水杨酰肼 、 2,6-二甲氧基苯甲酰氯 在 三乙胺 作用下， 以 乙腈 为溶剂， 反应 27.0h， 以73%的产率得到N'-(2-hydroxybenzoyl)-2,6-dimethoxybenzohydrazide
  参考文献：
  名称：

  Spectral Luminescent Properties of 2-Aryl-5-(2,6-dimethoxyphenyl)-1H-1,3,4-oxadiazoles

  摘要：

  2-Aryl-5-(2,6-dimethoxyphenyl)-1H-1,3,4-oxadiazoles were synthesized by cyclization reaction of benzoylbenzohydrazides in SOCl2, and their spectral luminescent properties were studied. The oxadiazoles containing phenyl or o-methoxyphenyl substituents in the position 2 were shown to luminesce with a high quantum yield in polar and nonpolar solvents. The replacement of these substituents by 2-hydroxyphenyl group led to oxadiazole intensely emitting only in highly polar aprotic DMSO.

  DOI：

  10.1134/s107036321802024x

文献信息

• A dodecanuclear metallamacrocycle having a multidentate bridging ligand in two different binding modes
  作者：Xinfang Liu、Wenlong Liu、Kyungjin Lee、Mira Park、Hyeong-Cheol Ri、Ghyung Hwa Kim、Myoung Soo Lah

  DOI：10.1039/b810711d

  日期：——

  The reaction of Mn(OAc)2·4H2O with 2,6-dimethoxybenzoylsalicylhydrazide (H3dmbshz) leads to a dodecanuclear manganese metallamacrocycle [Mn12(dmbshz)12(EtOH)6], 1. The successive manganese centers are connected by the hydrazide N–N groups of the ligands in an alternating pentadentate binding mode, hexadentate binding mode. The alternation results in two alternating chelation modes around the metal centers, a tridentate–tridentate chelation mode and a bidentate–tridentate chelation mode. The metal ions in 1 are in a ⋯(AAΔBCAΛB)(AAΔBCAΛB)⋯ chiral sequence, the alternation of the chiralities expanding the cyclic ring system to a 36-membered dodecanuclear manganese metallamacrocyclic ring system with S6 point group symmetry.

  Mn(OAc)2·4H2O与2,6-二甲氧基苯甲酰水杨酰肼（H3dmbshz）反应，生成十二核锰金属大环[Mn12(dmbshz)12(EtOH)6]，1。连续的锰中心通过配体的肼N-N基团以交替的五齿配位模式和六齿配位模式连接。这种交替作用在金属中心周围形成两种交替的螯合模式，即三齿-三齿螯合模式和二齿-三齿螯合模式。1中的金属离子呈⋯(AAΔBCAΛB)(AAΔBCAΛB)⋯手性序列，手性的交替将环状系统扩展为具有S6点群对称性的36元十二核锰金属大环系统。