o-Diurfurylidenimido-benzol | 15419-92-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: o-Diurfurylidenimido-benzol
• 英文别名: fur-o-phdn；1,2-Benzenediamine, N,N'-bis(2-furanylmethylene)-；1-(furan-2-yl)-N-[2-(furan-2-ylmethylideneamino)phenyl]methanimine
• CAS: 15419-92-8
• 化学式: C₁₆H₁₂N₂O₂
• 分子量: 264.283
• InChiKey: QBUWHHYUEUIEST-UHFFFAOYSA-N

物化性质

• 熔点：
  78 °C(Solv: ethanol (64-17-5))
• 沸点：
  456.5±30.0 °C(Predicted)
• 密度：
  1.16±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  o-Diurfurylidenimido-benzol 在 对甲苯磺酸 作用下， 以 neat (no solvent) 为溶剂， 以90%的产率得到2-(呋喃-2-基)-1-(呋喃-2-基甲基)苯并咪唑
  参考文献：
  名称：

  Facile Synthesis of 1,2-Disubstituted Benzimidazoles Usingp-Toluenesulfonic Acid through Grinding Method

  摘要：

  An efficient synthetic method for the highly selective synthesis of pharmacologically active 1,2-disubstituted benzimidazole derivatives fromo-phenylenediamine and various aromatic aldehydes catalyzed byp-toluenesulfonic acid through grinding under solvent-free condition is described. The reaction requires the catalyst only during the conversion of intermediateN,N '-dibenzylidene-o-phenylenediamine into the desired product. The products were obtained within a short time with good yields by using only a mortar and pestle, which makes the proposed method convenient and cost-effective.

  DOI：

  10.1134/s1070428020090201
• 作为产物：
  描述：

  糠醛 、 邻苯二胺 在 γ-maghemite-silica nanocomposite from 20 mg FeCl3/g silica activated 作用下， 以 neat (no solvent) 为溶剂， 生成 o-Diurfurylidenimido-benzol
  参考文献：
  名称：

  γ-Maghemite-silica nanocomposite: A green catalyst for diverse aromatic N-heterocycles

  摘要：

  gamma-Maghemite-silica nanocomposite has been applied as a green catalyst to synthesize variety of aromatic N-heterocycles under solvent free conditions. Characterization was done by modern analytical tools (UV, IR, AAS, DSC, EDXRF, powdered XRD, EPR, Mossbauer and TEM). Mild reaction conditions and recyclability have made the present protocol both environmentally and economically viable. (c) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2013.06.026

文献信息

• Synthesis, characterization and biological activity of some platinum(II) complexes with Schiff bases derived from salicylaldehyde, 2-furaldehyde and phenylenediamine
  作者：Akmal S. Gaballa、Mohsen S. Asker、Atiat S. Barakat、Said M. Teleb

  DOI：10.1016/j.saa.2006.06.031

  日期：2007.5

  complexes of Schiff bases derived from salicylaldehyde and 2-furaldehyde with o- and p-phenylenediamine were reported and characterized based on their elemental analyses, IR and UV-vis spectroscopy and thermal analyses (TGA). The complexes were found to have the general formula [Pt(L)(H(2)O)(2)]Cl(2) x nH(2)O (where n=0 for complexes 1, 3, 4; n=1 for complex 2. The data obtained show that Schiff bases were

  据报道，由水杨醛和2-呋喃甲醛制得的席夫碱与邻苯二胺和对苯二胺形成了四种铂（II）配合物，并根据其元素分析，红外和紫外可见光谱以及热分析（TGA）进行了表征。发现该配合物具有通式[Pt（L）（H（2）O）（2）] Cl（2）x nH（2）O（其中配合物1，3，4为n = 0; n = 1对于络合物2。获得的数据表明，席夫碱与中性形式的Pt（II）离子作为双齿配体相互作用，氧而不是氮是最可能的配位点，具有两个配位水的正方形平面几何结构提出了用于所有配合物的分子筛选自由配体及其金属配合物对以下细菌的抗菌活性：大肠杆菌，枯草芽孢杆菌，铜绿假单胞菌，金黄色葡萄球菌; 真菌黑曲霉，真菌 和酵母白念珠菌，酿酒酵母。活性数据表明，铂（II）配合物比针对一种或多种微生物的母体席夫碱配体更有效。