4'-(2-(2-ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid | 117420-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4'-(2-(2-ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid
• 英文别名: 4'-[2-(2-Ethoxyethoxy)ethoxy]biphenyl-4-carboxylic acid；4-[4-[2-(2-ethoxyethoxy)ethoxy]phenyl]benzoic acid
• CAS: 117420-29-8
• 化学式: C₁₉H₂₂O₅
• 分子量: 330.381
• InChiKey: RXAZEVUWUQOBEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4'-(2-(2-ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid 、 4,4'-(1,4-丁二氧基)双苯酚 在 氯化亚砜 作用下， 以 吡啶 为溶剂， 反应 4.67h， 以48%的产率得到E3PhC4PhE3 dimer
  参考文献：
  名称：

  4′-(2-(2-Ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid—a polar smectogen for amphipathic liquid crystals

  摘要：

  We describe a new calamitic smectogen and some of its esters with a three-block molecular architecture (polar oxyethylene chain, rigid biphenyl and non-polar aliphatic chain) which were characterised by a combination of optical, thermical. X-ray and computational techniques. The title Compound is a valuable smectogenic building block for amphipathic functional organic materials. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.002
• 作为产物：
  描述：

  methyl 4'-(2-(2-ethoxyethoxy)ethoxy)-[1,1'-biphenyl]-4-carboxylate 在 potassium hydroxide 作用下， 以 甲醇 、 水 为溶剂， 以70%的产率得到4'-(2-(2-ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid
  参考文献：
  名称：

  4′-(2-(2-Ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid—a polar smectogen for amphipathic liquid crystals

  摘要：

  We describe a new calamitic smectogen and some of its esters with a three-block molecular architecture (polar oxyethylene chain, rigid biphenyl and non-polar aliphatic chain) which were characterised by a combination of optical, thermical. X-ray and computational techniques. The title Compound is a valuable smectogenic building block for amphipathic functional organic materials. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.002

文献信息

• Liquid crystal compounds having ether tail moiety
  申请人：POLAROID CORPORATION

  公开号：EP0258578B1

  公开（公告）日：1993-01-07
• US5132041A
  申请人：——

  公开号：US5132041A

  公开（公告）日：1992-07-21
• 4′-(2-(2-Ethoxyethoxy)ethoxy)biphenyl-4-carboxylic acid—a polar smectogen for amphipathic liquid crystals
  作者：Rosana S. Montani、Claudia M. Hegguilustoy、Pablo G. Del Rosso、Bertrand Donnio、Daniel Guillon、Raúl O. Garay

  DOI：10.1016/j.tetlet.2009.07.002

  日期：2009.9

  We describe a new calamitic smectogen and some of its esters with a three-block molecular architecture (polar oxyethylene chain, rigid biphenyl and non-polar aliphatic chain) which were characterised by a combination of optical, thermical. X-ray and computational techniques. The title Compound is a valuable smectogenic building block for amphipathic functional organic materials. (C) 2009 Elsevier Ltd. All rights reserved.