dichlorothiophosphoric acid O-(3-ethyl-phenyl ester) | 92401-33-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dichlorothiophosphoric acid O-(3-ethyl-phenyl ester)
• 英文别名: Dichlorothiophosphorsaeure-O-(3-aethyl-phenylester)；Dichloro-(3-ethylphenoxy)-sulfanylidene-lambda5-phosphane；dichloro-(3-ethylphenoxy)-sulfanylidene-λ5-phosphane
• CAS: 92401-33-7
• 化学式: C₈H₉Cl₂OPS
• 分子量: 255.105
• InChiKey: QEXJECYKXMVCEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  41.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-乙基苯酚 在 甲烷 、 sulfur 、 三氯氧磷 、 三氯化磷 作用下， 生成 dichlorothiophosphoric acid O-(3-ethyl-phenyl ester)
  参考文献：
  名称：

  Aromatic Phosphorodichloridites and Phosphorodichloridothioates. I. Aryl Phosphorodichloridites

  摘要：

  DOI：

  10.1021/jo01105a025

文献信息

• US5804569A
  申请人：——

  公开号：US5804569A

  公开（公告）日：1998-09-08
• [EN] EXOCYCLIC-PHOSPHOETHANOLAMINES<br/>[FR] PHOSPHOETHANOLAMINES EXOCYCLIQUES
  申请人：CLARION PHARMACEUTICALS INC

  公开号：WO2000013690A1

  公开（公告）日：2000-03-16

  Disclosed are the use of certain cycloalkyl- and aryl-phosphoethanolamines as anti-inflammatory, anti-arrhythmic and local anesthetic agents. These therapeutically active cycloalkyl- and aryl-phosphoethanolamines are of the general Formula (I): R—O—PEA, wherein R is an unsubstituted or a substituted C5-7 cycloalkyl or an unsubstituted or substituted phenyl in which each substituent is hydrogen or an unsubstituted or substituted straight or branched C1-4 alkyl or C2-4 alkenyl, said substitution being one or more of C1-4 alkoxy, halo or cyano; and -O—PEA represents a phosphoethanolamine substituent. Also disclosed are intermediates for producing Formula (I) compounds.
• Aromatic Phosphorodichloridites and Phosphorodichloridothioates. I. Aryl Phosphorodichloridites
  作者：HENRY TOLKMITH

  DOI：10.1021/jo01105a025

  日期：1958.11