N,N'-dibenzyl-thiooxalamide | 20836-96-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N'-dibenzyl-thiooxalamide
• 英文别名: N,N'-Dibenzyl-thiooxalamid；N,N'-Dibenzyl-thiooxamsaeureamid；Thiooxalsaeure-dibenzylamid；N,N'-Dibenzyl-(thiooxamid)；N,N'-Dibenzylthiooxamid；N-benzyl-2-(benzylamino)-2-thioxoacetamide；N-benzyl-2-(benzylamino)-2-sulfanylideneacetamide
• CAS: 20836-96-8
• 化学式: C₁₆H₁₆N₂OS
• 分子量: 284.382
• InChiKey: IXPHFHCHCAPWJJ-UHFFFAOYSA-N

物化性质

• 熔点：
  118-119 °C(Solv: ethanol (64-17-5))
• 密度：
  1.206±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  73.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,N'-dibenzyl-thiooxalamide 在 potassium superoxide 、 4-nitrobenzene sulfonyl chloride 作用下， 以 乙腈 为溶剂， 反应 7.0h， 以92%的产率得到N,N'-二苄基草酰二胺
  参考文献：
  名称：

  使用由2-硝基苯磺酰氯和超氧阴离子生成的过氧硫中间体，将硫代羰基化合物新型脱硫为其相应的氧代衍生物。

  摘要：

  发现硫代羰基化合物（例如取代的硫脲，-硫代酰胺和-硫代氨基甲酸酯）与过氧硫中间体（3）反应，该中间体是通过用过氧化钾对2-硝基苯磺酰氯进行处理而生成的，以定量收率转化为相应的羰基化合物- 30°C在乙腈中。

  DOI：

  10.1016/s0040-4039(00)98517-4
• 作为产物：
  描述：

  N,N'-二苄基草酰二胺 在 吡啶 、 tetraphosphorus decasulfide 作用下， 生成 N,N'-dibenzyl-thiooxalamide
  参考文献：
  名称：

  612.巯基乙酸（巯基乙酸）的含氮衍生物制成的脱水化合物。第三部分 芳偶氮化合物

  摘要：

  DOI：

  10.1039/jr9560003189

文献信息

• Syntheses of<i>N</i>-Substituted Carbamimidoylformic Acids
  作者：Juji Yoshimura、Kunihiko Fujimori、Yuichi Sugiyama、Hiroaki Ando

  DOI：10.1246/bcsj.44.3131

  日期：1971.11

  conditions used. The presence of heavy metal ions in the reaction system caused an extensive decomposition of 9, however, the substitution proceeded smoothly by treatment of alkyl- and aryl-ammonium N-unsubstituted- or N-substituted-thiooxamidate in methanol with mercuric oxide or lead oxide to give in a good yield 6 or N,N-disubstituted-carbamimidoylformic acid, respectively.

  研究了 N-取代的氨基甲酰甲酸 (6) 的几种合成方法。其中，1-羧基乙氧基甲酰亚胺乙酯或硫代草酰胺乙酯与胺缩合，然后部分水解得到不成功的结果，除了后者反应中的苄胺的情况。根据所使用的条件，在水中用烷基胺直接取代硫代草酰胺酸钾 (9) 以相当好的收率得到 6、钾和/或烷基铵 N-取代的硫代草酰胺酸。反应体系中重金属离子的存在导致了 9 的广泛分解，然而，通过用氧化汞或氧化铅在甲醇中处理烷基铵和芳基铵 N-未取代或 N-取代的硫代草酰胺，取代过程顺利进行分别以良好的产率得到 6 或 N,N-二取代的氨基甲酰甲酸。
• Non-toxic corrosion-protection pigments based on manganese
  申请人：——

  公开号：US20040011252A1

  公开（公告）日：2004-01-22

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well-founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

  以锰为基础的缓蚀颜料含有三价或四价锰/价稳定剂复合物。一种无机或有机材料可用于稳定三价或四价锰离子，从而形成一种可少量溶解、溶解度低或不溶于水的化合物，具体取决于预期用途。选择特定的稳定剂是为了控制三价锰或四价锰在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。锰/价稳定剂组合的选择是基于锰配位化学的基本原理。文中介绍了许多锰价稳定剂组合，其性能与传统的六价铬或四价铅体系相当。需要强调的是，提供本摘要是为了符合要求提供摘要的规则，以便检索者或其他读者快速确定技术公开的主题。提交本摘要的前提是，本摘要不用于解释或限制权利要求的范围或含义。
• Non-toxic corrosion-protection pigments based on rare earth elements
  申请人：——

  公开号：US20040104377A1

  公开（公告）日：2004-06-03

  A corrosion-inhibiting pigment comprising a rare earth element and a valence stabilizer combinded to form a rare earth/valence stabilizer complex. The rare earth element is selected from cerium, terbium, praseodymium, or a combination thereof, and at least one rare earth element is in the tetravalent oxidation state. An inorganic or organic material is used to stabilize the tetravalent rare earth ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of tetravalent cerium, terbium, or praseodymium during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Many rare earth-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.

  一种缓蚀颜料，由稀土元素和价态稳定剂结合形成稀土/价态稳定剂复合物。稀土元素选自铈、铽、镨或它们的组合，至少有一种稀土元素处于四价氧化态。使用无机或有机材料来稳定四价稀土离子，以形成稀溶于水的化合物。选择特定的稳定剂是为了控制四价铈、铽或镨在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。本文介绍了许多稀土-价稳定剂组合，其性能可与传统的六价铬体系媲美。
• 234. Syntheses of thio-oxamides and thioamides by extensions of the Kindler reaction
  作者：Brian Milligan、J. M. Swan

  DOI：10.1039/jr9610001194

  日期：——
• Unexpected reactions of dithiodiglycolic acid: isolation of a novel seven-membered ring system based on a 2-amino derivative of 7-oxo-6,7-dihydro-[1,4,5]oxadithiepine
  作者：Min Li、Robert S Wu、Jane Tsai、Salvatore J Salamone

  DOI：10.1016/s0040-4039(02)00922-x

  日期：2002.7

  A novel seven-membered ring was unexpectedly isolated from the coupling of dithiodiglycolic acid with 2.2 equiv. Of N-hydroxysuccinimide, followed by addition of 0.25 equiv. of methyl (4-aminomethyl)benzoate hydrochloride (2) in the presence of 2 equiv. of triethylamine. (C) 2002 Published by Elsevier Science Ltd.