N-tert-butyl-2-(phenylselanyl)butan-1-amine | 831200-68-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-tert-butyl-2-(phenylselanyl)butan-1-amine
• 英文别名: 1-Butanamine, N-(1,1-dimethylethyl)-2-(phenylseleno)-；N-tert-butyl-2-phenylselanylbutan-1-amine
• CAS: 831200-68-1
• 化学式: C₁₄H₂₃NSe
• 分子量: 284.303
• InChiKey: ROTIAMRJHBTDDV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-phenylselanylbutanal 在 sodium cyanoborohydride 、 magnesium sulfate 、 溶剂黄146 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 4.17h， 生成 N-tert-butyl-2-(phenylselanyl)butan-1-amine
  参考文献：
  名称：

  α-Phenylselanyl imines: preparation of β-phenylselanyl amines and original synthesis of allylaziridines

  摘要：

  Resorting to suitable methods, a wide variety of alpha-phenylselanyl imines 2-5 were prepared from alpha-phenylselanyl aldehydes and alpha-phenylselanyl ketones 1. These compounds were reduced to afford beta-phenylselanyl amines 6-9. Our experimental conditions have limited the well known deselenenylation side-reaction occurring with most hydrides. On the other hand, the reaction of alpha-phenylselanyl imines 2 with organometallics led to the expected addition products only in the case of allylated derivatives. Depending on the temperature, either alpha-phenylselanyl amines 11 or unexpected allylaziridines 12 were recovered. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.10.065

文献信息

• α-Phenylselanyl imines: preparation of β-phenylselanyl amines and original synthesis of allylaziridines
  作者：Catherine Miniejew、Francis Outurquin、Xavier Pannecoucke

  DOI：10.1016/j.tet.2004.10.065

  日期：2005.1

  Resorting to suitable methods, a wide variety of alpha-phenylselanyl imines 2-5 were prepared from alpha-phenylselanyl aldehydes and alpha-phenylselanyl ketones 1. These compounds were reduced to afford beta-phenylselanyl amines 6-9. Our experimental conditions have limited the well known deselenenylation side-reaction occurring with most hydrides. On the other hand, the reaction of alpha-phenylselanyl imines 2 with organometallics led to the expected addition products only in the case of allylated derivatives. Depending on the temperature, either alpha-phenylselanyl amines 11 or unexpected allylaziridines 12 were recovered. (C) 2004 Elsevier Ltd. All rights reserved.