4-methyl-piperazine-1-carbothioic acid m-anisidide | 109185-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-piperazine-1-carbothioic acid m-anisidide
• 英文别名: 4-Methyl-piperazin-1-thiocarbonsaeure-m-anisidid；N-(3-methoxyphenyl)-4-methylpiperazine-1-carbothioamide
• CAS: 109185-53-7
• 化学式: C₁₃H₁₉N₃OS
• mdl: MFCD03140339
• 分子量: 265.379
• InChiKey: YQTZGTXLTMZRBB-UHFFFAOYSA-N

物化性质

• 溶解度：
  >39.8 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.461
• 拓扑面积：
  59.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  间氨基苯甲醚 在 ammonium hydroxide 、 乙醚 作用下， 生成 4-methyl-piperazine-1-carbothioic acid m-anisidide
  参考文献：
  名称：

  Tung et al., Huaxue Xuebao/Acta Chimica Sinica, 1957, vol. 23, p. 455,457

  摘要：

  DOI：

文献信息

• Anti-Arenaviral Compounds
  申请人：Amberg Sean M.

  公开号：US20120308519A1

  公开（公告）日：2012-12-06

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• ANTI-ARENAVIRAL COMPOUNDS
  申请人：SIGA TECHNOLOGIES, INC.,

  公开号：US20140301979A1

  公开（公告）日：2014-10-09

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• US8791110B2
  申请人：——

  公开号：US8791110B2

  公开（公告）日：2014-07-29
• Tung et al., Huaxue Xuebao/Acta Chimica Sinica, 1957, vol. 23, p. 455,457
  作者：Tung et al.

  DOI：——

  日期：——