3-(3-羟基-4-亚硝基-N-丙苯胺)丙磺酸 | 80459-15-0

• 物质功能分类: 分析化学 - 标准品 - 滴定标准品
• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 3-(3-羟基-4-亚硝基-N-丙苯胺)丙磺酸
• 中文别名: 2-亚硝基-5-[N-正丙基-N-(3-磺丙基)氨基]苯酚；3-(3-羟基-4-亚硝基-N-丙基苯胺)丙磺酸；3-(3-羟基-4-亚硝基-正丙氨基)丙磺酸
• 英文名称: 2-nitroso-5-(N-propyl-3-sulfopropylamino)phenol
• 英文别名: 3-(3-Hydroxy-4-nitroso-N-propylanilino)propanesulfonic acid；3-(3-hydroxy-4-nitroso-N-propylanilino)propane-1-sulfonic acid
• CAS: 80459-15-0
• 化学式: C₁₂H₁₈N₂O₅S
• 分子量: 302.351
• InChiKey: FNTOMPCYJCXKDL-UHFFFAOYSA-N

物化性质

• 熔点：
  165～170℃ (dec.)
• 密度：
  1.34±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  116
• 氢给体数：
  2
• 氢受体数：
  7

安全信息

• 安全说明：
  S22,S24/25
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  thulia 、 3-(3-羟基-4-亚硝基-N-丙苯胺)丙磺酸 在 盐酸 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  2-亚硝基-5-(N-丙基-3-磺丙基氨基)苯酚的钪、钇和镧系离子络合物的稳定性研究

  摘要：

  由 2-亚硝基-5-(N-丙基-3-磺丙基氨基)苯酚 (NPSAP:H2L) 与三价钪、钇和镧系元素（但不是钷）形成的 1:1 复合物的稳定性常数已通过电位测定法确定离子强度为 0.1 的硝酸钾水溶液和 25 °C。1:1 配合物的稳定性常数随着镧系元素原子序数的增加而增加，而钆则略有下降。在所研究的金属配合物中，钪的 1:1 配合物的稳定性常数最高，而钇配合物的稳定性常数介于铈和镨配合物之间。

  DOI：

  10.1246/bcsj.61.2639

文献信息

• Method of colorimetry and reagent for use therein
  申请人：——

  公开号：US20040142406A1

  公开（公告）日：2004-07-22

  The present invention provides a calorimetric method that can perform a simple and reliable analysis in a short time. The method includes transferring an electron from an analyte to a coloring reagent that produces color by reduction via a mediator by using an oxidoreductase; and performing qualitative or quantitative analysis of the analyte by measuring color produced in the coloring reagent. The enzyme reaction of this method is a single stage reaction, and the color production reaction occurs via the mediator. Therefore, the measurement can be performed in a short time. Since this reaction requires neither hydrogen peroxide nor oxygen, the measured values are highly reliable.

  本发明提供了一种热量计法，可以在短时间内进行简单可靠的分析。该方法包括使用氧化还原酶将电子从待分析物转移至染色试剂，通过介质还原产生颜色，并通过测量染色试剂中产生的颜色进行待分析物的定性或定量分析。该方法的酶反应是单阶段反应，颜色产生反应通过介质进行。因此，可在短时间内进行测量。由于该反应既不需要过氧化氢也不需要氧气，因此测量结果非常可靠。
• AIR BAG GAS GENERATING AGENT
  申请人：OTSUKA KAGAKU KABUSHIKI KAISHA

  公开号：EP0763512A1

  公开（公告）日：1997-03-19

  An object of this invention is to provide an air bag azide-free gas generating composition which can pronouncedly reduce the concentrations of toxic components in the after gas, especially both concentrations of CO and NOx while retaining the desired advantages of azide-free gas generating compositions. The air bag gas generating composition of the invention is an azide-free gas generating composition comprising a nitrogen-containing organic compound and an oxidizing agent as active components, and further contains, as a burning catalyst, at least one metallic oxide selected from the group consisting of molybdenum oxides, tungsten oxides and metallic oxides having a BET specific surface area of at least 5 m2/g.

  本发明的目的是提供一种气囊无氮气体发生组合物，它可以明显降低尾气中有毒成分的浓度，特别是一氧化碳和氮氧化物的浓度，同时保留了无氮气体发生组合物所需的优点。本发明的气囊气体发生组合物是一种无叠氮气体发生组合物，包括作为活性成分的含氮有机化合物和氧化剂，以及作为燃烧催化剂的至少一种金属氧化物，这些金属氧化物选自钼氧化物、钨氧化物和 BET 比表面积至少为 5 m2/g 的金属氧化物。
• METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE
  申请人：KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU

  公开号：EP0860695A1

  公开（公告）日：1998-08-26

  A method of measuring an analyte, comprising a step of measuring a detectable substance by using a reaction system including a formation reaction of the detectable substance based on a chemical reaction of the analyte contained in a sample, wherein a layered inorganic compound is caused to exist in the reaction system including the formation reaction of the detectable substance, whereby high-sensitivity measurement is made possible, the detectable substance can be stabilized to improve accuracy of the measurement, a rate of a chemical reaction is increased to enable quick measurement, and high-sensitivity measurement is made possible even in a reaction system which forms an insoluble substance. Also, it can be provided an analytical testing piece for measuring an analyte, by measuring a detectable substance by using a reaction system including a formation reaction of the detectable substance based on a chemical reaction of the analyte contained in a sample, wherein the testing piece comprises at least one test portion having a detection portion for detecting the detectable substance and contains a layered inorganic compound at least in the test portion, whereby diffusion and elution of a dyestuff or the like is prevented, more sensitive and accurate simple analysis is made possible, and easy handling is possible.

  一种测量被分析物的方法，包括以下步骤：根据样品中含有的被分析物的化学反应，使用包括可检测物质的形成反应的反应系统测量可检测物质，其中在包括可检测物质的形成反应的反应系统中导致层状无机化合物的存在、从而实现高灵敏度测量，稳定可检测物质以提高测量精度，提高化学反应速率以实现快速测量，即使在形成不溶性物质的反应体系中也能实现高灵敏度测量。此外，还可以提供一种用于测量被分析物的分析检测件，通过使用反应系统测量可检测物质，该反应系统包括基于样品中所含被分析物的化学反应的可检测物质的形成反应，其中检测件包括至少一个测试部分，该测试部分具有用于检测可检测物质的检测部分，并且至少在测试部分中包含分层无机化合物，从而防止染料或类似物的扩散和洗脱，实现更灵敏、更准确的简单分析，并且易于处理。
• SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT
  申请人：ARKRAY, Inc.

  公开号：EP1271143A1

  公开（公告）日：2003-01-02

  A test strip having the capability of separating blood cells from whole blood, wherein it has a porous reagent layer comprising beads, an inorganic gel and a reagent that causes a detectable reaction with a substance to be detected, and a substrate that supports the reagent layer, wherein the beads are adhered to each other with the inorganic gel, and interstices are formed between the beads to trap a solid. The test strip can thus be used for separating blood cells from a whole blood including blood cells and plasma and detecting a substance to be detected, such as glucose, contained in plasma. The use of the test strip allows the measurement of a substance to be detected even by measurement of a transmitted light, the exhibition of good oxygen permeability, and thus can be used for measuring a substance to be detected with improved accuracy.

  一种能从全血中分离血细胞的试纸，它具有一个多孔试剂层，该试剂层由微珠、无机凝胶和能与待检测物质发生可检测反应的试剂组成，以及一个支撑试剂层的基板，其中微珠与无机凝胶相互粘附，微珠之间形成间隙以吸附固体。因此，该试纸可用于从包括血细胞和血浆在内的全血中分离出血细胞，并检测血浆中的待检测物质，如葡萄糖。使用该试纸甚至可以通过透射光的测量来检测某种物质，显示出良好的透氧性，从而可以更准确地测量某种待检测物质。
• METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN
  申请人：ARKRAY, Inc.

  公开号：EP1457572A1

  公开（公告）日：2004-09-15

  The present invention provides a colorimetric method that can perform a simple and reliable analysis in a short time. The method includes transferring an electron from an analyte to a coloring reagent that produces color by reduction via a mediator by using an oxidoreductase; and performing qualitative or quantitative analysis of the analyte by measuring color produced in the coloring reagent. The enzyme reaction of this method is a single stage reaction, and the color production reaction occurs via the mediator. Therefore, the measurement can be performed in a short time. Since this reaction requires neither hydrogen peroxide nor oxygen, the measured values are highly reliable.

  本发明提供了一种比色法，可在短时间内进行简单可靠的分析。该方法包括利用氧化还原酶将电子从被分析物转移到通过介质还原产生颜色的显色试剂中；以及通过测量显色试剂中产生的颜色对被分析物进行定性或定量分析。该方法中的酶反应是一个单级反应，而颜色生成反应是通过介质发生的。因此，测量可在短时间内完成。由于该反应既不需要过氧化氢，也不需要氧气，因此测量值非常可靠。