3-methyl-4-phenylfurazan | 10349-09-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methyl-4-phenylfurazan
• 英文别名: 3-phenyl-4-methylfurazan；3-methyl-4-phenyl-furazan；Methyl-phenyl-furazan；3-Phenyl-4-methyl-1,2,5-oxadiazol；3-methyl-4-phenyl-1,2,5-oxadiazole
• CAS: 10349-09-4
• 化学式: C₉H₈N₂O
• mdl: MFCD01201489
• 分子量: 160.175
• InChiKey: NJFVZLLKYNGWAE-UHFFFAOYSA-N

物化性质

• 熔点：
  2 °C
• 沸点：
  145 °C(Press: 16 Torr)
• 密度：
  1.142±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  38.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-methyl-4-phenylfurazan 在 硫酸 、 硝酸 作用下， 反应 1.0h， 以97%的产率得到3-(2,4-Dinitro-phenyl)-4-methyl-furazan
  参考文献：
  名称：

  3-苯基-4-取代的呋喃酮的硝化方向

  摘要：

  DOI：

  10.1007/bf00513282
• 作为产物：
  描述：

  phenylmethylglyoxime diacetate 在 sodium hydroxide 作用下， 反应 2.0h， 生成 3-methyl-4-phenylfurazan
  参考文献：
  名称：

  3-苯基-4-取代的呋喃酮的硝化方向

  摘要：

  DOI：

  10.1007/bf00513282

文献信息

• Nitrophenyl derivatives of the furazan and furoxan ring systems
  作者：R. Calvino、B. Ferrarotti、A. Gasco、A. Serafino

  DOI：10.1002/jhet.5570200554

  日期：1983.9

  The preparation of some nitrophenyl derivatives of the furazan and furoxan ring systems is reported. The results of an antimicrobial screening on these compounds are also briefly discussed.

  据报道制备了呋喃山和呋喃烷环系统的一些硝基苯基衍生物。还简要讨论了对这些化合物进行抗菌筛选的结果。
• INHIBITORS OF IAP
  申请人：Ndubaku Chudi

  公开号：US20110046066A1

  公开（公告）日：2011-02-24

  The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula (I), and G, X 1 , X 2 , R 1 , R 2 , R 3 , R 4 , R 4 ′, R 5 , R a , R b , and R c are as described herein.

  这项发明提供了新型IAP抑制剂，可作为治疗剂用于治疗恶性肿瘤，其中化合物具有一般式(I)，并且G、X1、X2、R1、R2、R3、R4、R4'、R5、Ra、Rb和Rc如本文所述。
• Inhibitors of IAP
  申请人：Cohen Frederick

  公开号：US20070299052A1

  公开（公告）日：2007-12-27

  The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: wherein X, Y, A, R 1 , R 2 , R 3 , R 4 , R 4 ′, R 5 , R 5 ′, R 6 and R 6 ′ are as described herein.

  该发明提供了新型的IAP抑制剂，可用作治疗恶性肿瘤的治疗剂，其中化合物具有一般式I，其中X、Y、A、R1、R2、R3、R4、R4'、R5、R5'、R6和R6'如本文所述。
• Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same
  申请人：Kawakami Sachiko

  公开号：US20090153041A1

  公开（公告）日：2009-06-18

  A quinoxaline-based, new bipolar organic compound is provided, and a light emitting element using the quinoxaline-based compound is demonstrated. The quinoxaline derivative of the invention has a structure in which carbon at one or both of the 2-position and the 3-position of the quinoxaline unit are bonded, via an arylene group, with an amine unit which has a substituted or unsubstituted five-membered ring or a substituted or unsubstituted condensed ring containing a five-membered ring structure. The quinoxaline-based compound was proven to possess bipolar characteristics in view of carrier transportation, which allows the fabrication of a light emitting element and an electronic appliance with a low driving voltage and low power consumption.

  本发明提供了一种基于喹喔啉的新型双极有机化合物，并演示了使用该基于喹喔啉的化合物的发光元件。该发明的喹喔啉衍生物具有结构，在其中，喹喔啉单元的2位和/或3位的碳通过芳基烃基团与一种含有取代或未取代的五元环或含有五元环结构的取代或未取代的缩合环的胺单元键合。基于喹喔啉的化合物被证明具有双极特性，具有载流子传输的特性，这允许制造具有低驱动电压和低功耗的发光元件和电子设备。
• Quinoxaline derivative, and light emitting element, licht emitting device and electronic appliance using the same
  申请人：SEMICONDUCTOR ENERGY LABORATORY CO., LTD.

  公开号：EP2067778A1

  公开（公告）日：2009-06-10

  A quinoxaline-based, new bipolar organic compound is provided, and a light emitting element using the quinoxaline-based compound is demonstrated. The quinoxaline derivative of the invention has a structure in which carbon at one or both of the 2-position and the 3-position of the quinoxaline unit are bonded, via an arylene group, with an amine unit which has a substituted or unsubstituted five-membered ring or a substituted or unsubstituted condensed ring containing a five-membered ring structure. The quinoxaline-based compound was proven to possess bipolar characteristics in view of carrier transportation, which allows the fabrication of a light emitting element and an electronic appliance with a low driving voltage and low power consumption.

  本发明提供了一种基于喹喔啉的新型双极有机化合物，并展示了一种使用该基于喹喔啉的化合物的发光元件。本发明的喹喔啉衍生物具有这样的结构：喹喔啉单元 2 位和 3 位中的一个或两个位置上的碳通过芳烯基与具有取代或未取代五元环或含有五元环结构的取代或未取代缩合环的胺单元键合。这种基于喹喔啉的化合物被证明在载流子传输方面具有双极特性，因此可以制造低驱动电压和低功耗的发光元件和电子设备。