6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine | 144900-62-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine
• 英文别名: 4-Methyl-2-[6-[6-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]pyridin-2-yl]-1,3-thiazole；4-methyl-2-[6-[6-(4-methyl-1,3-thiazol-2-yl)pyridin-2-yl]pyridin-2-yl]-1,3-thiazole
• CAS: 144900-62-9
• 化学式: C₁₈H₁₄N₄S₂
• 分子量: 350.468
• InChiKey: NXIJCIYXEXVYEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  108
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  copper(II) perchlorate hexahydrate 、 6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine 以 硝基甲烷 为溶剂， 生成 [(6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine)aqua(perchlorato)copper(II)] perchlorate
  参考文献：
  名称：

  潜在的四齿吡啶基-噻唑配体6,6'-双（4-甲基噻唑-2-基）-2,2'-联吡啶与CoII，NiII，CuII，CdII，HgII，CuI和AgI的溶液和固态络合物

  摘要：

  潜在的四齿N供体配体6,6'-双（4-甲基噻唑-2-基）-2,2'-联吡啶（L1）与过渡金属离子CoII，NiII，CuII，CdII和HgII的反应导致形成单核[M（L1）] 2+配合物，其中平面配体通过所有四个N-供体与金属配位。相反，L1与CuI和AgI单阳离子反应，得到双核双链螺旋物种[M2（L1）2] 2+（其中M = CuI或AgI），其中配体分配为两个双双齿吡啶基-噻唑螯合单元允许每个配体桥接两个金属中心。X射线晶体学，电喷雾质谱和NMR光谱表明，当M ＝ CoII，NiII，CuII，CdII和HgII时，[Mn（L1）m] z +（其中n ＝ 1，m ＝ 1和z ＝ 2）的配合物。 n = 2，m = 2，z = 2，当M = CuI时），将其固态结构保留在溶液中。相反，尽管1 H NMR研究表明等摩尔量的Ag（X）（其中）和L1（在硝基甲烷或乙腈中）的结合会导致溶液中形

  DOI：

  10.1016/j.ica.2005.03.002
• 作为产物：
  描述：

  6,6'-二溴-2,2'-联吡啶 在 硫化氢 、 氨 、 copper(l) cyanide 作用下， 以 四氢呋喃 为溶剂， 反应 111.0h， 生成 6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine
  参考文献：
  名称：

  Novel tetra- and hexa-dentate ligands from 6,6′-dicyano-2,2′-bipyridine

  摘要：

  A simple, direct route from 2,2'-bipyridine to 6,6'-dicyano-2,2'-bipyridine and its conversion to the 6,6'-dithiocarboxamide and various novel tetra- and hexa-dentate ligands such as the 6,6'-bis(4-methyl-thiazol-2-yl) and 6,6'-bis[4-(2-pyridyl)thiazol-2-yl] derivatives have been established. Diaqua[6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine]zinc(II) bis(trifluoromethanesulfonate) has been prepared and its crystal structure determined. The tetra-heterocyclic ligand is planar, binding through two bipyridine nitrogen atoms and, more weakly, through two thiazolyl nitrogen atoms to zinc(ii) which is in a distorted octahedral environment.

  DOI：

  10.1039/dt9920003015

文献信息

• Solution and solid-state complexes of the potentially tetradentate pyridyl-thiazole ligand 6,6′-bis(4-methylthiazol-2-yl)-2,2′-bipyridine with CoII, NiII, CuII, CdII, HgII, CuI and AgI
  作者：Thomas Riis-Johannessen、John C. Jeffery、Alex P.H. Robson、Craig R. Rice、Lindsay P. Harding

  DOI：10.1016/j.ica.2005.03.002

  日期：2005.6

  with the transition metal dications CoII, NiII, CuII, CdII and HgII results in the formation of mononuclear [M(L1)]2+ complexes, in which a planar ligand coordinates to the metals via all four N-donors. In contrast, reaction of L1 with CuI and AgI monocations, affords dinuclear double stranded helicate species [M2(L1)2]2+ (where M = CuI or AgI), in which partitioning of the ligand into two bis-bidentate

  潜在的四齿N供体配体6,6'-双（4-甲基噻唑-2-基）-2,2'-联吡啶（L1）与过渡金属离子CoII，NiII，CuII，CdII和HgII的反应导致形成单核[M（L1）] 2+配合物，其中平面配体通过所有四个N-供体与金属配位。相反，L1与CuI和AgI单阳离子反应，得到双核双链螺旋物种[M2（L1）2] 2+（其中M = CuI或AgI），其中配体分配为两个双双齿吡啶基-噻唑螯合单元允许每个配体桥接两个金属中心。X射线晶体学，电喷雾质谱和NMR光谱表明，当M ＝ CoII，NiII，CuII，CdII和HgII时，[Mn（L1）m] z +（其中n ＝ 1，m ＝ 1和z ＝ 2）的配合物。 n = 2，m = 2，z = 2，当M = CuI时），将其固态结构保留在溶液中。相反，尽管1 H NMR研究表明等摩尔量的Ag（X）（其中）和L1（在硝基甲烷或乙腈中）的结合会导致溶液中形
• Novel tetra- and hexa-dentate ligands from 6,6′-dicyano-2,2′-bipyridine
  作者：Paul N. W. Baxter、Joseph A. Connor、W. Bernd Schweizer、John D. Wallis

  DOI：10.1039/dt9920003015

  日期：——

  A simple, direct route from 2,2'-bipyridine to 6,6'-dicyano-2,2'-bipyridine and its conversion to the 6,6'-dithiocarboxamide and various novel tetra- and hexa-dentate ligands such as the 6,6'-bis(4-methyl-thiazol-2-yl) and 6,6'-bis[4-(2-pyridyl)thiazol-2-yl] derivatives have been established. Diaqua[6,6'-bis(4-methylthiazol-2-yl)-2,2'-bipyridine]zinc(II) bis(trifluoromethanesulfonate) has been prepared and its crystal structure determined. The tetra-heterocyclic ligand is planar, binding through two bipyridine nitrogen atoms and, more weakly, through two thiazolyl nitrogen atoms to zinc(ii) which is in a distorted octahedral environment.