9-[N-[3-(methacrylamido)propylamino]methyl]-10-[N-[2-(tert-butoxycarbonyl)ethylamino]methyl]-anthracene | 1030832-19-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 9-[N-[3-(methacrylamido)propylamino]methyl]-10-[N-[2-(tert-butoxycarbonyl)ethylamino]methyl]-anthracene
• 英文别名: Tert-butyl 3-[[10-[[3-(2-methylprop-2-enoylamino)propylamino]methyl]anthracen-9-yl]methylamino]propanoate
• CAS: 1030832-19-9
• 化学式: C₃₀H₃₉N₃O₃
• 分子量: 489.658
• InChiKey: HSWCMCNIMPBHKY-UHFFFAOYSA-N

物化性质

• 沸点：
  697.4±55.0 °C(Predicted)
• 密度：
  1.104±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  36
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  79.5
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-(2-(bromomethyl)-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 、 9-[N-[3-(methacrylamido)propylamino]methyl]-10-[N-[2-(tert-butoxycarbonyl)ethylamino]methyl]-anthracene 在 N,N-二异丙基乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 生成 9-[N-[6-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolano)-3-nitrobenzyl]-N-[3-(methacrylamido)propylamino]methyl]-10-[N-[6-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolano)-3-nitrobenzyl]-N-[2-(tert-butoxycarbonyl)ethylamino]methyl]anthracene
  参考文献：
  名称：

  WO2008/66921

  摘要：

  公开号：

文献信息

• OXIDATION RESISTANT INDICATOR MOLECULES
  申请人：Colvin Arthur E.

  公开号：US20080145944A1

  公开（公告）日：2008-06-19

  Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups.

  本发明揭示了具有增强氧化稳定性的化合物。这些化合物具有含有芳基硼酸残基的分子，该芳基上含有一个或多个电子提取基团，使得该分子相对于不含有该电子提取基团的相应分子具有增强的氧化抗性。
• Oxidation Resistant Indicator Molecules
  申请人：Colvin, JR. Arthur E.

  公开号：US20110081727A1

  公开（公告）日：2011-04-07

  Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation resistance as compared to a corresponding molecule without the one or more electron withdrawing groups.

  本发明揭示了具有增强氧化稳定性的化合物。这些化合物具有含有芳基硼酸残基的分子，该残基上含有一个或多个电子吸引基团，从而使分子相对于没有这些电子吸引基团的相应分子具有增强的氧化抗性。
• Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone
  申请人：——

  公开号：US20030082663A1

  公开（公告）日：2003-05-01

  Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.

  用于测定样品中葡萄糖的存在或浓度的组合物和方法，样品中可能还含有α-羟基酸或β-二酮。该方法使用的化合物至少有两个葡萄糖识别元素，其方向使该化合物与葡萄糖之间的相互作用比该化合物与α-羟基酸或β-二酮之间的相互作用更稳定，从而使α-羟基酸或β-二酮的存在不会对上述测定产生实质性干扰。
• DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE
  申请人：Sensors for Medicine and Science, Inc.

  公开号：EP1490359B1

  公开（公告）日：2010-05-19
• US6800451B2
  申请人：——

  公开号：US6800451B2

  公开（公告）日：2004-10-05