2-Propenoic acid, 2-methyl-, 3-hydroxy-6,8-disulfo-1-pyrenyl ester | 627870-12-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 2-Propenoic acid, 2-methyl-, 3-hydroxy-6,8-disulfo-1-pyrenyl ester
• 英文别名: 6-hydroxy-8-(2-methylprop-2-enoyloxy)pyrene-1,3-disulfonic acid
• CAS: 627870-12-6
• 化学式: C₂₀H₁₄O₉S₂
• 分子量: 462.5
• InChiKey: BGDUFOSNVLHNEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  172
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• POLYMER MATRIX FOR SENSING
  申请人：SciLogica Corp.

  公开号：EP3879273A1

  公开（公告）日：2021-09-15

  The invention relates to a polymer matrix for optical sensing of pH and/or carbon dioxide, and a process for producing the polymer matrix. Also discussed is an optical sensor for optical sensing of pH and/or carbon dioxide comprising the polymer matrix of the invention and an optical waveguide, and a method for making the optical sensor. The invention further provides a method of measuring the pH and/or the carbon dioxide content of a sample, using the sensor of the invention. The optical sensor is useful in measuring the pH and/or the carbon dioxide content of biological samples such as blood. The polymer matrix comprises a fluorophore (e.g. HPTS), a positively charged counter-ion moiety and a polymeric support, wherein either the fluorophore or the counter-ion moiety is covalently bound to the polymeric support by a polymer linking moiety.

  本发明涉及一种用于 pH 值和/或二氧化碳光学传感的聚合物基体，以及生产该聚合物基体的工艺。本发明还讨论了一种光学感测 pH 值和/或二氧化碳的光学传感器，该传感器由本发明的聚合物基体和光波导组成，还讨论了一种制造该光学传感器的方法。本发明进一步提供了一种使用本发明传感器测量样品中 pH 值和/或二氧化碳含量的方法。该光学传感器可用于测量血液等生物样本的 pH 值和/或二氧化碳含量。聚合物基质包括荧光团（如 HPTS）、带正电荷的反离子分子和聚合物支架，其中荧光团或反离子分子通过聚合物连接分子与聚合物支架共价结合。
• OPTICAL COMPONENT
  申请人：SciLogica Corp.

  公开号：US20210333213A1

  公开（公告）日：2021-10-28

  The invention is concerned with methods for producing a useful and highly uniform optical component which is useful in the construction of an optical sensor. Also discussed are the optical component itself, an optical sensor comprising the optical component, a process for producing the optical sensor and a process for detecting and/or quantifying the amount of an analyte in a sample using the optical sensor.
• [EN] POLYMER MATRIX FOR CO2 SENSING<br/>[FR] MATRICE POLYMÈRE POUR LA DÉTECTION DE CO2
  申请人：SCILOGICA CORP

  公开号：WO2021181088A1

  公开（公告）日：2021-09-16

  The invention relates to a polymer matrix for optical sensing of carbon dioxide, and a process for producing the polymer matrix. Also discussed is an optical sensor for optical sensing of carbon dioxide comprising the polymer matrix of the invention, and a method for making the optical sensor. The invention further provides a method of measuring the carbon dioxide content of a sample, using the sensor of the invention. The optical sensor is useful in measuring the carbon dioxide content of biological samples such as blood. The polymer matrix comprises a fluorophore, a positively charged counter-ion moiety and a polymeric support, wherein either the fluorophore or the counter-ion moiety is covalently bound to the polymeric support by a polymer linking moiety.