2-(perfluoro-1'-methyl-2'-oxapentyl)thiophene | 133414-72-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 2-(perfluoro-1'-methyl-2'-oxapentyl)thiophene
• 英文别名: 2-[1,2,2,2-Tetrafluoro-1-(1,1,2,2,3,3,3-heptafluoropropoxy)ethyl]thiophene
• CAS: 133414-72-9
• 化学式: C₉H₃F₁₁OS
• 分子量: 368.171
• InChiKey: BUFYVOVLWBMMBV-UHFFFAOYSA-N

物化性质

• 沸点：
  186.5±40.0 °C(Predicted)
• 密度：
  1.610±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  37.5
• 氢给体数：
  0
• 氢受体数：
  13

反应信息

• 作为产物：
  描述：

  噻吩 、 bis(perfluoro-2-N-propoxypropionyl)peroxide 以 1,1,2-三氯三氟乙烷（CFC-113） 为溶剂， 反应 5.0h， 以62%的产率得到2-(perfluoro-1'-methyl-2'-oxapentyl)thiophene
  参考文献：
  名称：

  Synthesis of aromatic compounds containing perfluoro-oxa-alkyl groups

  摘要：

  Perfluoro-oxa-alkanoyl peroxides[[C3F7O(CF(CF3)CF2O)nCF(CF3)CO2]2, n = 0, 1, 2] smoothly reacted with thiophene and furan under mild conditions to affor 2-perfluoro-oxa-alkylthiophenes and furnas in good yields. Perfluoro-oxa-alkylations of benzene and pyrrole were also found to proceed by the use of these peroxides. Furthermore, these peroxides were found to be applied to direct aromatic perfluoro-oxa-alkylations of polystyrene.

  DOI：

  10.1016/s0022-1139(00)80311-5

文献信息

• JPH0429969A
  申请人：——

  公开号：JPH0429969A

  公开（公告）日：1992-01-31
• Synthesis of aromatic compounds containing perfluoro-oxa-alkyl groups
  作者：Hideo Sawada、Masaharu Nakayama

  DOI：10.1016/s0022-1139(00)80311-5

  日期：1991.1

  Perfluoro-oxa-alkanoyl peroxides[[C3F7O(CF(CF3)CF2O)nCF(CF3)CO2]2, n = 0, 1, 2] smoothly reacted with thiophene and furan under mild conditions to affor 2-perfluoro-oxa-alkylthiophenes and furnas in good yields. Perfluoro-oxa-alkylations of benzene and pyrrole were also found to proceed by the use of these peroxides. Furthermore, these peroxides were found to be applied to direct aromatic perfluoro-oxa-alkylations of polystyrene.