[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-prop-2-enyloxolan-2-yl]methyl dihydrogen phosphate | 474237-09-7

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-prop-2-enyloxolan-2-yl]methyl dihydrogen phosphate
• CAS: 474237-09-7
• 化学式: C₁₂H₁₇N₂O₈P
• 分子量: 348.25
• InChiKey: YBIORRPKKRHSQH-DEKFOEGESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  146
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Antibodies having specificity for nucleic acids
  申请人：——

  公开号：US20030228590A1

  公开（公告）日：2003-12-11

  The present invention relates to antibodies, antibody conjugates, and compositions thereof, methods of antibody synthesis, and applications of antibodies useful for detecting the presence of nucleic acid molecules in vivo, such as in a clinical setting. The antibodies of the invention are also useful as screening agents which allow the selection of candidate therapeutic molecules for optimum bioavailability and/or activity, and as delivery agents for cell and tissue specific delivery of nucleic acid molecules.

  本发明涉及抗体、抗体共轭物及其组合物、抗体合成方法以及抗体在检测体内（如临床环境中）核酸分子存在方面的应用。本发明的抗体还可用作筛选剂，筛选出最佳生物利用度和/或活性的候选治疗分子，还可用作细胞和组织特异性递送核酸分子的递送剂。
• US7071311B2
  申请人：——

  公开号：US7071311B2

  公开（公告）日：2006-07-04