Thiophene, 2,2',2''-ethylidynetris- | 129982-95-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: Thiophene, 2,2',2''-ethylidynetris-
• 英文别名: 2-(1,1-dithiophen-2-ylethyl)thiophene
• CAS: 129982-95-2
• 化学式: C₁₄H₁₂S₃
• 分子量: 276.4
• InChiKey: DGBWNNVUWYHSIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  84.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Riboswitches and methods and compositions for use of and with riboswitches
  申请人：Yale University

  公开号：EP2426218A1

  公开（公告）日：2012-03-07

  Riboswitches are targets for antibiotics and other small molecule therapies. Riboswitches and portions thereof can be used to regulate the expression or function of RNA molecules and other elements and molecules. Riboswitches and portions thereof can be used in a variety of other methods to, for example, identify or detect compounds. Compounds can be used to stimulate, active, inhibit and/or inactivate the riboswitch. Riboswitches and portions thereof, both alone and in combination with other nucleic acids, can be used in a variety of constructs and RNA molecules and can be encoded by nucleic acids.

  核糖开关是抗生素和其他小分子疗法的靶标。核糖开关及其部分可用于调节 RNA 分子及其他元素和分子的表达或功能。核糖开关及其部分可用于多种其它方法，例如识别或检测化合物。化合物可用于刺激、激活、抑制和/或使核糖开关失活。核糖开关及其部分，无论是单独使用还是与其它核酸结合使用，都可用于各种构建物和 RNA 分子，并可由核酸编码。
• METHODS AND COMPOSITIONS FOR THE USE OF LYSINE RIBOSWITCHES
  申请人：Yale University

  公开号：EP2061799A2

  公开（公告）日：2009-05-27
• PREQ1 RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH PREQ1 RIBOSWITCHES
  申请人：Yale University, Inc.

  公开号：EP2139909A1

  公开（公告）日：2010-01-06
• RIBOSWITCHES AND METHODS AND COMPOSITIONS FOR USE OF AND WITH RIBOSWITCHES
  申请人：Yale University

  公开号：EP2164996A2

  公开（公告）日：2010-03-24
• LYSINE RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH LYSINE RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH LYSINE RIBOSWITCHES
  申请人：Breaker Ronald R.

  公开号：US20100137440A1

  公开（公告）日：2010-06-03

  The lysine riboswitch is a target for antibiotics and other small molecule therapies. Compounds can be used to stimulate, active, inhibit and/or inactivate the lysine riboswitch.