tetramethyl-2,3,5,6 dihydro-2,5 benzo-b (1H) azepine | 92617-30-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: tetramethyl-2,3,5,6 dihydro-2,5 benzo-b (1H) azepine
• 英文别名: 2,3,5,6-tetramethyl-2,5-dihydro-1H-1-benzazepine；1H-1-Benzazepine, 2,5-dihydro-2,3,5,6-tetramethyl-
• CAS: 92617-30-6
• 化学式: C₁₄H₁₉N
• 分子量: 201.312
• InChiKey: AXSLWQBNRXIAKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tetramethyl-2,3,5,6 dihydro-2,5 benzo-b (1H) azepine 以 乙醇 、 水 为溶剂， 以45%的产率得到2,3,5,6-tetramethyl-5H-1-benzazepine
  参考文献：
  名称：

  Electrochemical oxidation of 2,5-dihydro-1h-1-benzazepines : Synthesis of 5H-1-benzazepines

  摘要：

  Formation of 5H-1-benzazepines was observed after electrochemical oxidation of the title compounds in a flow cell at a graphite felt anode and in acetic buffer. In basic medium, coupling reaction also occurs leading to [2,5-dihydro-1H-1-benzazepin-1-yl]-5H-1-benzazepines. Oxidation mechanisms are discussed.

  DOI：

  10.1016/0040-4020(95)00536-h

文献信息

• Uriac, Philippe; Bonnic, Jean; Huet, Jean, Journal of Chemical Research, Miniprint, 1984, # 5, p. 1441 - 1465
  作者：Uriac, Philippe、Bonnic, Jean、Huet, Jean

  DOI：——

  日期：——
• Electrochemical oxidation of 2,5-dihydro-1h-1-benzazepines : Synthesis of 5H-1-benzazepines
  作者：B. Kharraz、P. Uriac、L. Toupet、J.P. Hurvois、C. Moinet、A. Tallec

  DOI：10.1016/0040-4020(95)00536-h

  日期：1995.8

  Formation of 5H-1-benzazepines was observed after electrochemical oxidation of the title compounds in a flow cell at a graphite felt anode and in acetic buffer. In basic medium, coupling reaction also occurs leading to [2,5-dihydro-1H-1-benzazepin-1-yl]-5H-1-benzazepines. Oxidation mechanisms are discussed.