(5S)-1-diphenylphosphanyl-5-(diphenylphosphanyloxymethyl)pyrrolidin-2-one | 153650-38-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (5S)-1-diphenylphosphanyl-5-(diphenylphosphanyloxymethyl)pyrrolidin-2-one
• CAS: 153650-38-5
• 化学式: C₂₉H₂₇NO₂P₂
• 分子量: 483.486
• InChiKey: GOZDSEDVWKGMSV-DEOSSOPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  34
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II) 、 (5S)-1-diphenylphosphanyl-5-(diphenylphosphanyloxymethyl)pyrrolidin-2-one 以 正己烷 为溶剂， 以86%的产率得到[Ru[(S)-P(C6H5)2C4H5N(O)(CH2OP(C6H5)2)](η3-C4H7)2]
  参考文献：
  名称：

  Hapiot, Frederic; Agbossou, Francine; Meliet, Catherine, New Journal of Chemistry, 1997, vol. 21, # 11, p. 1161 - 1172

  摘要：

  DOI：
• 作为产物：
  描述：

  二苯基氯化膦 、 L-焦谷氨醇 在 三乙胺 作用下， 以 乙醚 为溶剂， 以80%的产率得到(5S)-1-diphenylphosphanyl-5-(diphenylphosphanyloxymethyl)pyrrolidin-2-one
  参考文献：
  名称：

  New alkylarylamidophosphinephosphinites as chiral diphosphines for asymmetric hydrogenation of activated keto compounds

  摘要：

  Syntheses of new easily accessible chiral alkylarylamidophosphinephosphinite chelating ligands are described. Their rhodium complexes [Rh(L2*)Cl]2 are highly effective precursors for the catalytic asymmetric hydrogenation of functionalized ketones. Ketopantoyllactone and N-benzylphenyl glyoxamide are converted to the corresponding alcohols up to 96 and 79.6 % ee respectively.

  DOI：

  10.1016/s0957-4166(00)80082-8

文献信息

• Naïli, Saïd; Carpentier, Jean-François; Agbossou, Francine, Organometallics, 1995, vol. 14, # 1, p. 401 - 406
  作者：Naïli, Saïd、Carpentier, Jean-François、Agbossou, Francine、Mortreux, André、Nowogrocki, Guy、Wignacourt, Jean-Pierre

  DOI：——

  日期：——
• New alkylarylamidophosphinephosphinites as chiral diphosphines for asymmetric hydrogenation of activated keto compounds
  作者：Alain Roucoux、Francine Agbossou、André Mortreux、Francis Petit

  DOI：10.1016/s0957-4166(00)80082-8

  日期：1993.11

  Syntheses of new easily accessible chiral alkylarylamidophosphinephosphinite chelating ligands are described. Their rhodium complexes [Rh(L2*)Cl]2 are highly effective precursors for the catalytic asymmetric hydrogenation of functionalized ketones. Ketopantoyllactone and N-benzylphenyl glyoxamide are converted to the corresponding alcohols up to 96 and 79.6 % ee respectively.
• Hapiot, Frederic; Agbossou, Francine; Meliet, Catherine, New Journal of Chemistry, 1997, vol. 21, # 11, p. 1161 - 1172
  作者：Hapiot, Frederic、Agbossou, Francine、Meliet, Catherine、Mortreux, Andre、Rosair, Georgina M.、Welch, Alan J.

  DOI：——

  日期：——