3-Amino-2-mercapto-benzoic acid | 71807-60-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-Amino-2-mercapto-benzoic acid
• 英文别名: o-aminothiophenolcarboxylic acid；Benzoic acid, 3-amino-2-mercapto-；3-amino-2-sulfanylbenzoic acid
• CAS: 71807-60-8
• 化学式: C₇H₇NO₂S
• 分子量: 169.204
• InChiKey: OBQCWOHPSPQUDZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.3
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  氢氧化钾 、 2-氨基-7-苯并噻唑羧酸甲酯 在 氮 、 ice 、 1,4-二氧六环 、 ice water 作用下， 以 水 、 1,4-二氧六环 为溶剂， 反应 0.33h， 以The title compound can be isolated from the filtrate by acidification to pH 5.5的产率得到3-Amino-2-mercapto-benzoic acid
  参考文献：
  名称：

  3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation

  摘要：

  公式I的化合物及其二硫化物和盐是制备具有杀菌和植物免疫作用的公式III化合物的重要中间产物。在公式I和III的化合物中：X是卤素，n为0、1、2或3；Z是CN、CO-A或CS-A，A是氢、卤素、OR1、SR2和N（R3）R4；R1到R4是氢、含有不超过8个碳原子的取代或未取代的开链、饱和或不饱和的碳氢基团，含有不超过10个碳原子的取代或未取代的环状、饱和或不饱和的碳氢基团，取代或未取代的苄基或苯乙基，含有不超过8个碳原子的取代或未取代的烷酰基团，取代或未取代的苯甲酰基团或取代或未取代的杂环基基团；或者R3和R4与它们所连接的氮原子一起，形成一个含有1-3个杂原子O、S和/或N的5-或6元取代或未取代的杂环基基团。描述了公式I化合物的制备方法。

  公开号：

  US06498265B2

文献信息

• Compositions for use in golf balls
  申请人：Bulpett A. David

  公开号：US20050245652A1

  公开（公告）日：2005-11-03

  A golf ball comprises a core, an outer cover layer, and, optionally, an intermediate layer disposed between the core and the outer cover layer. The outer cover layer may comprise a polyurethane or polyurea composition. At least one portion of the golf ball comprises a composition that enhances physical properties and/or performance characteristics (e.g., coefficient of restitution) of the golf ball. Preferably, the coefficient of restitution of the core is 0.8 or greater.

  高尔夫球由内核、外覆盖层和可选的中间层组成，外覆盖层可以包括聚氨酯或聚脲组成。高尔夫球的至少一部分包含一种增强物理特性和/或性能特征（例如反弹系数）的组合物。最好，内核的反弹系数为0.8或更高。
• O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid
  申请人：Siemens Aktiengesellschaft

  公开号：US20010056203A1

  公开（公告）日：2001-12-27

  The invention relates to novel o-aminophenolcarboxylic acids or o-aminothiophenolcarboxylic acids of the following structure 1 in which: A 1 to A 7 are—independently of one another—H, CH 3 , OCH 3 , CH 2 CH 3 or OCH 2 CH 3 ; T is O or S, and m is 0 or 1; Z is a carbocyclic or heterocyclic aromatic radical.

  本发明涉及以下结构的新型o-氨基苯酚羧酸或o-氨基噻吩羧酸1： 其中，A1至A7独立地为H、CH3、O 、CH2 或OCH2 ；T为O或S，m为0或1；Z为一个碳环或杂环芳香基团。
• 3-amino-2-mercaptobenzoic acid derivatives and processes for their
  申请人：Novartis Corporation

  公开号：US05770758A1

  公开（公告）日：1998-06-23

  Compounds of the formula I ##STR1## and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III ##STR2## In the compounds of the formulae I and III: X is halogen, n is 0,1,2 or 3; Z is CN, CO-A or CS-A, A is hydrogen, halogen, OR.sub.1, SR.sub.2 and N(R.sub.3)R.sub.4 ; R.sub.1 to R .sub.4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or R.sub.3 and R.sub.4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O,S and/or N. Processes for the preparation of compounds of the formula I are described.

  式I的化合物##STR1##及其二硫化物和盐是制备具有杀菌和植物免疫作用的化合物的重要中间体，该化合物的式III为##STR2##在式I和III的化合物中：X为卤素，n为0、1、2或3；Z为CN、CO-A或CS-A，A为氢、卤素、OR.sub.1、SR.sub.2和N（R.sub.3）R.sub.4；R.sub.1至R.sub.4为氢、含有不超过8个碳原子的取代或未取代的开链、饱和或不饱和的烃基、含有不超过10个碳原子的取代或未取代的环状、饱和或不饱和的烃基、取代或未取代的苄基或苯乙基、含有不超过8个碳原子的取代或未取代的烷酰基、取代或未取代的苯甲酰基或取代或未取代的杂环基基；或R.sub.3和R.sub.4与它们键合的氮原子一起，是1-3个杂原子O、S和/或N的取代或未取代的5-或6元杂环基。描述了制备式I的化合物的过程。
• 3-Amino-2-mercaptobenzoic acid derivatives and processes for their
  申请人：Novartis Corp.

  公开号：US05847147A1

  公开（公告）日：1998-12-08

  Compounds of the formula I ##STR1## and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III ##STR2## In the compounds of the formulae I and III: X is halogen, n is 0, 1, 2 or 3; Z is CN, CO-A or CS-A, A is hydrogen, halogen, OR.sub.1, SR.sub.2 and N(R.sub.3)R.sub.4 ; R.sub.1 to R.sub.4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or R.sub.3 and R.sub.4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O, S and/or N. Processes for the preparation of compounds of the formula I are described.

  公式I的化合物##STR1##及其二硫化物和盐是制备具有杀菌和植物免疫作用的化合物的重要中间体，公式III如下：##STR2## 在公式I和III的化合物中：X是卤素，n为0、1、2或3；Z为CN、CO-A或CS-A，A为氢、卤素、OR.sub.1、SR.sub.2和N(R.sub.3)R.sub.4；R.sub.1至R.sub.4为氢、含有不超过8个碳原子的取代或未取代的开链、饱和或不饱和的烃基，含有不超过10个碳原子的取代或未取代的环状、饱和或不饱和的烃基，取代或未取代的苄基或苯乙基，含有不超过8个碳原子的取代或未取代的烷酰基，取代或未取代的苯甲酰基或取代或未取代的杂环基基团；或R.sub.3和R.sub.4与它们连接的氮原子一起，是含有1-3个杂原子O、S和/或N的5-或6成员的取代或未取代的杂环基基团。描述了公式I的化合物的制备方法。
• COMPOSITIONS FOR USE IN GOLF BALLS
  申请人：Sullivan Michael J.

  公开号：US20080227567A1

  公开（公告）日：2008-09-18

  A golf ball comprises a core, an outer cover layer, and, optionally, an intermediate layer disposed between the core and the outer cover layer. The outer cover layer may comprise a polyurethane or polyurea composition. At least one portion of the golf ball comprises a composition that enhances physical properties and/or performance characteristics (e.g., coefficient of restitution) of the golf ball. Preferably, the coefficient of restitution of the core is 0.8 or greater.

  一个高尔夫球包括一个核心、一个外覆盖层，以及可选的介质层，介质层位于核心和外覆盖层之间。外覆盖层可能包括聚氨酯或聚脲组成。高尔夫球的至少一部分包含一种增强高尔夫球物理性能和/或性能特征（例如反弹系数）的组成。最好，核心的反弹系数为0.8或更高。