甲基辛弗林盐酸盐

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

甲基辛弗林盐酸盐

中文别名

——

英文名称

hydron;4-[1-hydroxy-2-(methylamino)propyl]phenol;chloride

英文别名

——

CAS

——

化学式

C10H16ClNO2

mdl

——

分子量

217.69

InChiKey

ICBZSKCTKKUQSY-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

1.46
重原子数：

14
可旋转键数：

3
环数：

1.0
sp3杂化的碳原子比例：

0.4
拓扑面积：

52.5
氢给体数：

4
氢受体数：

3

文献信息

Process for the production of optically active beta-amino alcohols

申请人：——

公开号：US20040091981A1

公开（公告）日：2004-05-13

A process for producing an optical active &bgr;-amino alcohol, the method comprising the step of allowing at least one microorganism selected from the group consisting of microorganisms belonging to the genus Morganella and others, to act on an enantiomeric mixture of an &agr;-aminoketone or a salt thereof having the general formula (I): 1 to produce an optical active &bgr;-amino alcohol with the desired optical activity having the general formula (II) described below in a high yield as well as in a highly selective manner: 2

一种制备光学活性&bgr;-氨基醇的方法，包括以下步骤：让至少一种选择自属于摩根氏菌属和其他微生物组的微生物作用于具有通式(I)的&agr;-氨基酮或其盐的对映异构体混合物，以高产率和高选择性地产生具有所需光学活性的&bgr;-氨基醇，其通式为(II)：
PROCESS FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS

申请人：Daiichi Fine Chemical Co., Ltd.

公开号：EP1273665A1

公开（公告）日：2003-01-08

A process for producing an optical active β-amino alcohol, the method comprising the step of allowing at least one microorganism selected from the group consisting of microorganisms belonging to the genus Morganella and others, to act on an enantiomeric mixture of an α-aminoketone or a salt thereof having the general formula (I): to produce an optical active β-amino alcohol with the desired optical activity having the general formula (II) described below in a high yield as well as in a highly selective manner:

一种生产光学活性 β-氨基醇的方法，该方法包括以下步骤：让至少一种选自摩根菌属微生物及其他微生物组成的微生物作用于具有通式（I）的α-氨基酮或其盐的对映体混合物：以高产率和高选择性的方式生产出具有所需光学活性的 β-氨基醇，其通式（II）如下所述：
An otorhinological drug delivery device

申请人：Schering Oy

公开号：EP1438942A1

公开（公告）日：2004-07-21

The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elastomer composition selected from the group consisting of poly(dimethylsiloxane), a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms of the siloxane units, a siloxane-based elastomer comprising poly(alkylene oxide) groups and mixtures thereof.

本发明涉及一种包含至少一种药用活性剂的耳鼻喉给药装置。根据本发明，该装置包括一个包含所述至少一种药物活性剂的芯体，其中所述芯体由弹性体组合物制成，该弹性体组合物选自聚（二甲基硅氧烷）、硅氧烷基弹性体（包含连接到硅氧烷单元S原子上的3,3,3-三氟丙基）、硅氧烷基弹性体（包含聚（环氧烷）基团）及其混合物组成的组。
Cloning and characterization of slc26a7 and slc26a9 anion exchangers

申请人：Mount, Jr. B David

公开号：US20050176945A1

公开（公告）日：2005-08-11

Isolated nucleic acids encoding SLC26A7 and SLC26A9 anion transporter polypeptides, recombinantly expressed SLC26A7 and SLC26A9 anion transporter polypeptides, heterologous expression systems for recombinant expression of SLC26A7 and SLC26A9 anion transporter polypeptides, assay methods employing the same, and methods for modulation of anion transport activity.

编码 SLC26A7 和 SLC26A9 阴离子转运体多肽的分离核酸、重组表达的 SLC26A7 和 SLC26A9 阴离子转运体多肽、重组表达 SLC26A7 和 SLC26A9 阴离子转运体多肽的异源表达系统、采用上述核酸的检测方法以及调节阴离子转运活性的方法。
Cloning and characterization of slc26a6, slc26a1, and slc26a2 anion exchangers

申请人：Mount B. David

公开号：US20060014940A1

公开（公告）日：2006-01-19

Isolated nucleic acids encoding SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, recombinantly expressed SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, heterologous expression systems for recombinant expression of SLC26A6, SLC26A1, and SLC26A2 anion transporter polypeptides, assay methods employing the same, and methods for modulation of anion transport activity.

编码 SLC26A6、SLC26A1 和 SLC26A2 阴离子转运体多肽的分离核酸，重组表达的 SLC26A6、SLC26A1 和 SLC26A2 阴离子转运体多肽，用于重组表达 SLC26A6、SLC26A1 和 SLC26A2 阴离子转运体多肽的异源表达系统，使用这些多肽的检测方法，以及调节阴离子转运活性的方法。