1-Benzyloxy-4,5-dimethoxy-2-(1-methyl-allyl)-benzene | 302324-78-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Benzyloxy-4,5-dimethoxy-2-(1-methyl-allyl)-benzene
• 英文别名: Benzene, 1,2-dimethoxy-4-(1-methyl-2-propenyl)-5-(phenylmethoxy)-；1-but-3-en-2-yl-4,5-dimethoxy-2-phenylmethoxybenzene
• CAS: 302324-78-3
• 化学式: C₁₉H₂₂O₃
• 分子量: 298.382
• InChiKey: BAALSQIHRYZFQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-Benzyloxy-4,5-dimethoxy-2-(1-methyl-allyl)-benzene 在 Pd black-(G) 氢气 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以100%的产率得到2-sec-Butyl-4,5-dimethoxy-phenol
  参考文献：
  名称：

  Pd black deposited on polypropylene sheet as a highly selective catalyst for hydrogenation of alkenes

  摘要：

  A catalyst deposited on a polypropylene sheet having an activity of almost the same level as commercially available Pd black and capable of promoting hydrogenolysis-free hydrogenation was developed. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00551-3

文献信息

• Hydrogenolysis-free Hydrogenation by Pd Black Powder Catalyst
  作者：Shojiro Maki、Makiko Okawa、Ryo Matsui、Takashi Hirano、Haruki Niwa

  DOI：10.1055/s-2001-17485

  日期：——

  A new general method of hydrogenolysis-free hydrogenation using a commercially available Pd black powder catalyst has developed.

  一种新的通用氢化方法已经开发，采用商业化可得的Pd黑粉催化剂，无需氢解。
• Selective Alkene Hydrogenation with Atomic Hydrogen Permeating Through a Pd Sheet Electrode
  作者：Shojiro Maki、Yasuhiro Harada、Takashi Hirano、Haruki Niwa、Yasuki Yoshida、Setsuro Ogata、Shuji Nakamatsu、Hiroshi Inoue、Chiaki Iwakura

  DOI：10.1080/00397910008087273

  日期：2000.10

  Chemoselective hydrogenation of olefinic double bonds without concomitant hydrogenolysis of allylic and benzylic C-O linkages was performed successfully by the aid of active hydrogen permeated through a Pd sheet electrode.
• Effect of solvent and hydrogen during selective hydrogenation
  作者：Shojiro Maki、Yasuhiro Harada、Ryo Matsui、Makiko Okawa、Takashi Hirano、Haruki Niwa、Megumi Koizumi、Yoshinori Nishiki、Tsuneto Furuta、Hiroshi Inoue、Chiaki Iwakura

  DOI：10.1016/s0040-4039(01)01787-7

  日期：2001.11

  Described is the solvent effect for the chemoselective hydrogenation of alkenes having a benzyloxy group (Bn-O-) using a hydrogenation system employing atomic hydrogen permeating through a Pd sheet electrode. (C) 2001 Elsevier Science Ltd. All rights reserved.
• Pd black deposited on polypropylene sheet as a highly selective catalyst for hydrogenation of alkenes
  作者：Shojiro Maki、Makiko Okawa、Toshimichi Makii、Takashi Hirano、Haruki Niwa

  DOI：10.1016/s0040-4039(03)00551-3

  日期：2003.4

  A catalyst deposited on a polypropylene sheet having an activity of almost the same level as commercially available Pd black and capable of promoting hydrogenolysis-free hydrogenation was developed. (C) 2003 Elsevier Science Ltd. All rights reserved.