n-hexadecyl phenyl hydrogen phosphate | 161003-29-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: n-hexadecyl phenyl hydrogen phosphate
• 英文别名: Hexadecyl phenyl hydrogen phosphate
• CAS: 161003-29-8
• 化学式: C₂₂H₃₉O₄P
• 分子量: 398.523
• InChiKey: NGZWYWSVUKVDIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  27
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  n-hexadecyl phenyl hydrogen phosphate 、 O-<4,6-diacetoxy-2-azido-2-deoxy-3-O-<(R)-1'-(methoxycarbonyl)ethyl>-β-D-glucopyranosyl>-trichloroacetimidate 以 甲苯 为溶剂， 反应 1.0h， 以66%的产率得到4,6-di-O-acetyl-2-azido-2-deoxy-3-O-<(R)-1'-(methoxycarbonyl)ethyl>-α-D-glucopyranosyl n-hexadecyl phenyl phosphate
  参考文献：
  名称：

  尿酸和C-1同源α-D-葡萄糖衍生物的合成作为潜在的细菌转糖基化酶抑制剂

  摘要：

  掺入类脂质基团的山mura酸的磷酸衍生物已被合成为潜在的细菌转糖基化酶抑制剂。路易斯酸催化的不饱和烷基硅烷加成至甲基α-D-吡喃葡萄糖苷，然后进行氧化裂解，已被用于提供葡萄糖的C-1同系物的途径。还描述了将α-D-葡萄糖甲膦酸转化为衍生自脂质样基团的酯。

  DOI：

  10.1016/0040-4020(95)00415-5
• 作为产物：
  描述：

  1-十六烷醇 、 二氯磷酸苯酯 以 二氯甲烷 为溶剂， 生成 n-hexadecyl phenyl hydrogen phosphate
  参考文献：
  名称：

  尿酸和C-1同源α-D-葡萄糖衍生物的合成作为潜在的细菌转糖基化酶抑制剂

  摘要：

  掺入类脂质基团的山mura酸的磷酸衍生物已被合成为潜在的细菌转糖基化酶抑制剂。路易斯酸催化的不饱和烷基硅烷加成至甲基α-D-吡喃葡萄糖苷，然后进行氧化裂解，已被用于提供葡萄糖的C-1同系物的途径。还描述了将α-D-葡萄糖甲膦酸转化为衍生自脂质样基团的酯。

  DOI：

  10.1016/0040-4020(95)00415-5

文献信息

• COMPOSITION FOR HYDROPHILIC CURED PRODUCT
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3081578A1

  公开（公告）日：2016-10-19

  Objects of the present invention are to provide a composition which can easily give cured products enriched with hydrophilic groups at the surface, and a composition which can give cured products while ensuring that the surface is enriched with hydrophilic groups which are hardly concentrated at the surface by conventional methods; to provide cured products obtained from such compositions; to provide a composition which is suited for producing cured products having high and long-lasting hydrophilicity and also having high surface smoothness; and to provide a cured product obtained from the composition. A monolayer film is fabricated which includes a crosslinked resin obtained by polymerizing a composition including a compound (I) having at least one hydrophilic group selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and at least one functional group with a polymerizable carbon-carbon double bond (wherein the number of the functional groups with a polymerizable carbon-carbon double bond is one when the hydrophilic group is a hydroxyl-containing group); a compound (II) having two or more functional groups with a polymerizable carbon-carbon double bond (wherein the compound may have a hydroxyl group but is free from anionic hydrophilic groups and cationic hydrophilic groups); and at least one compound selected from a surfactant (III) having a hydrophilic moiety including an anionic hydrophilic group, a cationic hydrophilic group or two or more hydroxyl groups, and a hydrophobic moiety including an organic residue, and a compound (IV) having a siloxane bond and a molecular weight of 200 to 1,000,000 (wherein the surfactant (III) and the compound (IV) have no polymerizable carbon-carbon double bonds). The monolayer film has a gradient of hydrophilic group concentration (Sa/Da) of not less than 1.1 wherein Sa is the surface concentration of at least one type of hydrophilic groups selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and Da is the deep concentration of the hydrophilic groups at 1/2 of the thickness of the monolayer film.

  本发明的目的是提供一种组合物，该组合物可以很容易地得到表面富含亲水基团的固化产品，以及一种组合物，该组合物可以在得到固化产品的同时确保表面富含亲水基团，而通过传统方法，亲水基团很难集中在表面上；提供由这种组合物得到的固化产品；提供一种组合物，该组合物适合生产具有高且持久亲水性的固化产品，同时还具有高表面光滑度；以及提供由该组合物得到的固化产品。本发明制备了一种单层膜，该单层膜包括通过聚合一种组合物而获得的交联树脂，该组合物包括一种化合物 (I)，该化合物具有至少一个亲水基团，该亲水基团选自阴离子亲水基团、阳离子亲水基团和羟基，以及至少一个具有可聚合碳碳双键的官能团（其中当亲水基团为含羟基基团时，具有可聚合碳碳双键的官能团的数目为一个）；具有两个或两个以上具有可聚合碳碳双键的官能团的化合物 (II)（其中该化合物可具有羟基，但不含阴离子亲水基团和阳离子亲水基团）；以及至少一种选自表面活性剂（III）的化合物，该表面活性剂具有包括阴离子亲水基团、阳离子亲水基团或两个或多个羟基在内的亲水分子，以及包括有机残留物在内的疏水分子，以及具有硅氧烷键且分子量在 200-1,000,000 之间的化合物（IV）（其中表面活性剂（III）和化合物（IV）不具有可聚合的碳碳双键）。单层膜的亲水基团浓度梯度（Sa/Da）不小于 1.1，其中 Sa 是选自阴离子亲水基团、阳离子亲水基团和羟基的至少一种亲水基团的表面浓度，Da 是亲水基团在单层膜厚度的 1/2 处的深度浓度。
• MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3263635A1

  公开（公告）日：2018-01-03

  The purpose of the present invention is to provide a modified acrylic resin cured product, particularly, a modified acrylic resin film, having excellent lubricity and excellent transparency, and a laminate including the modified acrylic resin film. The modified acrylic resin cured product (C) according to the present invention is obtained by treating the surface of a cured product (X) including an acrylic resin by using a compound (A) containing, in each molecule, one or more anionic hydrophilic groups forming an ion pair with an onium ion of an amino silicone, and one or more groups selected from the group consisting of a group containing a polymerizable carbon-carbon double bond, an amino group, a mercapto group and a hydroxy group.

  本发明的目的是提供一种改性丙烯酸树脂固化物，特别是改性丙烯酸树脂薄膜，它具有极佳的润滑性和极佳的透明度，以及一种包括改性丙烯酸树脂薄膜的层压板。根据本发明的改性丙烯酸树脂固化物（C）是通过使用化合物（A）处理包括丙烯酸树脂的固化物（X）的表面而获得的，化合物（A）在每个分子中含有一个或多个阴离子亲水基团，这些基团与氨基硅的鎓离子形成离子对，还含有一个或多个基团，这些基团选自由含有可聚合碳碳双键的基团、氨基、巯基和羟基组成的组。
• Modified acrylic resin cured product, and laminate thereof, and production methods therefor
  申请人：MITSUI CHEMICALS, INC.

  公开号：US10428194B2

  公开（公告）日：2019-10-01

  The purpose of the present invention is to provide a modified acrylic resin cured product, particularly, a modified acrylic resin film, having excellent lubricity and excellent transparency, and a laminate including the modified acrylic resin film. The modified acrylic resin cured product (C) according to the present invention is obtained by treating the surface of a cured product (X) including an acrylic resin by using a compound (A) containing, in each molecule, one or more anionic hydrophilic groups forming an ion pair with an onium ion of an amino silicone, and one or more groups selected from the group consisting of a group containing a polymerizable carbon-carbon double bond, an amino group, a mercapto group and a hydroxy group.

  本发明的目的是提供一种改性丙烯酸树脂固化物，特别是改性丙烯酸树脂薄膜，它具有极佳的润滑性和极佳的透明度，以及一种包括改性丙烯酸树脂薄膜的层压板。根据本发明的改性丙烯酸树脂固化物（C）是通过使用化合物（A）处理包括丙烯酸树脂的固化物（X）的表面而获得的，化合物（A）在每个分子中含有一个或多个阴离子亲水基团，这些基团与氨基硅的鎓离子形成离子对，还含有一个或多个基团，这些基团选自由含有可聚合碳碳双键的基团、氨基、巯基和羟基组成的组。
• HYDROPHILIC CURABLE COMPOSITIONS
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20180163056A1

  公开（公告）日：2018-06-14

  A monolayer film which includes a crosslinked resin obtained by polymerizing a composition including compound (I) having at least one hydrophilic group selected from anionic hydrophilic groups, cationic hydrophilic groups and hydroxyl groups, and at least one functional group with a polymerizable carbon-carbon double bond wherein the number of the functional groups with a polymerizable carbon-carbon double bond is one when the hydrophilic group is a hydroxyl-containing group; compound (II) having two or more functional groups with a polymerizable carbon-carbon double bond; and at least one compound selected from a surfactant (III) having a hydrophilic moiety including an anionic hydrophilic group, a cationic hydrophilic group or two or more hydroxyl groups, and a hydrophobic moiety including an organic residue, and compound (IV) having a siloxane bond and a molecular weight of 200 to 1,000,000 wherein the surfactant (III) and the compound (IV) have no polymerizable carbon-carbon double bonds.
• Synthesis of derivatives of muramic acid and C-1 homologated α-D-glucose as potential inhibitors of bacterial transglycosylase
  作者：Gerald Brooks、Peter D. Edwards、Julia D.I. Hatto、Terence C. Smale、Robert Southgate

  DOI：10.1016/0040-4020(95)00415-5

  日期：1995.7

  Phosphate derivatives of muramic acid, incorporating a lipid-like group, have been synthesised as potential inhibitors of bacterial transglycosylase. The Lewis acid catalysed addition of unsaturated alkyl silanes to methyl α-D-glucopyranoside, followed by an oxidative cleavage, has been used to provide a route to C-1 homologues of glucose. Conversion of α-D-glucose methanephosphonic acid to esters derived

  掺入类脂质基团的山mura酸的磷酸衍生物已被合成为潜在的细菌转糖基化酶抑制剂。路易斯酸催化的不饱和烷基硅烷加成至甲基α-D-吡喃葡萄糖苷，然后进行氧化裂解，已被用于提供葡萄糖的C-1同系物的途径。还描述了将α-D-葡萄糖甲膦酸转化为衍生自脂质样基团的酯。