Glycerin-(2)-lactat | 21067-16-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: Glycerin-(2)-lactat
• 英文别名: glycerol monolactate；Glycerol 2-lactate；1,3-dihydroxypropan-2-yl 2-hydroxypropanoate
• CAS: 21067-16-3
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: FKDAUXUGSFYAOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME<br/>[FR] CATALYSEURS POUR LA TRANSFORMATION DE DIOXYDE DE CARBONE ET DE GLYCÉROL EN ACIDE FORMIQUE ET EN ACIDE LACTIQUE ET LEURS PROCÉDÉS DE FABRICATION
  申请人：UNIV GEORGE WASHINGTON

  公开号：WO2018213821A1

  公开（公告）日：2018-11-22

  Catalysts and methods for transformation of glycerol and a carbon feedstock, such as CO2, a carbonate salt or a bicarbonate salt, are described herein. Homogeneous catalysts include compounds of formula M[NHC-R-linker]aLbXc, where M is a transition metal, NHC is an N-heterocyclic carbene ligand, R is an alkyl or aryl group, linker is a polar group, L is a neutral ligand, X is an anionic ligand, a ranges from 1-3, b ranges from 0-3, and c ranges from 0-3. Heterogeneous catalysts include a solid support with a catalytically active compound immobilized on the solid support, where the catalytically active compound has the formula M[NHC-R-linker]aLbXc where M is a transition metal, NHC is an N-heterocyclic carbene ligand, R is an alkyl or aryl group; linker is a polar group, L is a neutral ligand, X is an anionic ligand, a ranges from 1-3, b ranges from 0-3, and c ranges from 0-3.

  本文描述了用于转化甘油和碳原料（如CO2、碳酸盐或碳酸氢盐）的催化剂和方法。均相催化剂包括具有M[NHC-R-linker]aLbXc式化合物的化合物，其中M是过渡金属，NHC是N-杂环卡宾配体，R是烷基或芳基，linker是极性基团，L是中性配体，X是阴离子配体，a范围为1-3，b范围为0-3，c范围为0-3。非均相催化剂包括具有固体支撑物的催化活性化合物固定在固体支撑物上，其中催化活性化合物具有M[NHC-R-linker]aLbXc式化合物，其中M是过渡金属，NHC是N-杂环卡宾配体，R是烷基或芳基；linker是极性基团，L是中性配体，X是阴离子配体，a范围为1-3，b范围为0-3，c范围为0-3。
• Topical Delivery System for Cosmetic and Pharmaceutical Agents
  申请人：Gupta K. Shyam

  公开号：US20060110415A1

  公开（公告）日：2006-05-25

  This invention relates to topical compositions containing esters of hydroxy acids and their application in the deep-penetration delivery of beneficial cosmetic and pharmaceutical agents.

  本发明涉及含有羟基酸酯的局部组成物，以及它们在深层渗透输送有益的化妆品和药物剂的应用。
• Topical Delivery System for Phytosterols
  申请人：GUPTA SHYAM K.

  公开号：US20090042846A1

  公开（公告）日：2009-02-12

  This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof; Wherein, n=0, 1, 2, or 3; and R=H, —CH 2 OH, —CH(OH)—CH 2 OH, —CH(OH)—CH(OH)—CH 2 OH; and R 1 =Substituent selected from a sapogenin, steroid, or terpenoid.

  本发明涉及公式（I）的植物甾醇糖酯，这些酯类适用于局部应用，并用于治疗皮肤状况，包括老年斑、痤疮、细胞抗氧化剂的丧失、胶原蛋白的丧失、皮肤柔韧性的丧失、皮肤柔软性的丧失、皮肤皱纹包括细纹、氧化、辐射损伤、基质金属蛋白酶的功能障碍、酪氨酸酶的功能障碍、自由基的损伤、紫外线的损伤、干燥皮肤、角化病、鱼鳞病、头皮屑、褐色斑点、角化病、黄褐斑、肝斑、色素斑点、眼圈黑色素沉着、皮肤色素沉着包括皮肤变黑、瑕疵、油性皮肤、疣、湿疹、瘙痒性皮肤、银屑病、炎症性皮肤病、局部炎症、角化异常、与衰老相关的皮肤变化、需要清洁剂、调理剂或治疗剂的指甲或皮肤，以及需要洗发水或护发素的头发或头皮，以及其组合；其中，n = 0、1、2或3；R = H、—CH2OH、—CH（OH）—CH2OH、—CH（OH）—CH（OH）—CH2OH；R1 = 从皂甙、类固醇或萜类中选择的取代基。
• Hard film composition for capsules
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP0600422A1

  公开（公告）日：1994-06-08

  A hard film composition for capsules, comprising a gelatin, and 3 to 10 % by weight of an ester of a fatty acid and glycerol or a polyglycerol added based on said gelatin. The capsules formed by the composition of the invention may not be embrittled even when the moisture in the capsule film is reduced by charging therein a hygroscopic drug, minimizing the liability of cracking or chipping, and thus preventing leakage of the drug contained therein to be caused by the damage of capsules.

  一种用于胶囊的硬膜组合物，由明胶和以所述明胶为基础添加的脂肪酸和甘油酯或聚甘油酯（按重量计）的 3%至 10%组成。由本发明的组合物形成的胶囊，即使在胶囊膜中加入吸湿性药物使其湿度降低时，也不会脆化，从而最大限度地减少了开裂或崩裂的可能性，并因此防止了因胶囊损坏而导致其中所含药物的泄漏。
• WHIPPED CREAM
  申请人：ASAHI DENKA KOGYO KABUSHIKI KAISHA

  公开号：EP1254605A1

  公开（公告）日：2002-11-06

  Whipped cream of the present invention contains substantially no spherical fat particles having a particle diameter of 1 µm or greater, or contains 10% or more of spherical fat particles having a particle diameter of 0.1 µm or smaller, or contains 20% by volume or more of spherical fat particles having a particle diameter of 0.4 µm or smaller.

  本发明的鲜奶油基本上不含颗粒直径为 1 微米或更大的球形脂肪颗粒，或含有 10% 或更多颗粒直径为 0.1 微米或更小的球形脂肪颗粒，或含有 20% 或更多体积的颗粒直径为 0.4 微米或更小的球形脂肪颗粒。