N-(3,5-Diazido-4-hydroxy-phenyl)-benzenesulfonamide | 918161-75-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3,5-Diazido-4-hydroxy-phenyl)-benzenesulfonamide
• 英文别名: N-(3,5-Diazido-4-hydroxyphenyl)benzenesulfonamide；N-(3,5-diazido-4-hydroxyphenyl)benzenesulfonamide
• CAS: 918161-75-8
• 化学式: C₁₂H₉N₇O₃S
• 分子量: 331.315
• InChiKey: LMQVNEZHSLHETD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  104
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  N-phenylsulfonyl-2-chloro-1,4-benzoquinone imine 在 sodium azide 作用下， 以 溶剂黄146 为溶剂， 生成 N-(3,5-Diazido-4-hydroxy-phenyl)-benzenesulfonamide 、 N-(3-Azido-5-chloro-4-hydroxy-phenyl)-benzenesulfonamide
  参考文献：
  名称：

  Reactivity of N-arylsulfonyl-1,4-benzoquinone imines. Reaction with hydrazoic acid

  摘要：

  N-Arylsulfonyl-2-halo-1,4-benzoquinone imines react with hydrazoic acid in boiling acetic acid via two pathways: the 1,4-addition and nucleophilic replacement of the halogen atom by an azido group, followed by the 1,4-addition of HN3. In the reaction of N-arylsulfonyl-2,6-dihalo-1,4-benzoquinone imines with hydrazoic acid, both halogen atoms are replaced by azido groups, while N-p-tolylsulfonyl-2-methyl-1,4-benzoquinone imine takes up HN3 molecule according to the 1,4-addition pattern.

  DOI：

  10.1134/s1070428006030110

文献信息

• Reactivity of N-arylsulfonyl-1,4-benzoquinone imines. Reaction with hydrazoic acid
  作者：A. P. Avdeenko、Yu. V. Menafova

  DOI：10.1134/s1070428006030110

  日期：2006.3

  N-Arylsulfonyl-2-halo-1,4-benzoquinone imines react with hydrazoic acid in boiling acetic acid via two pathways: the 1,4-addition and nucleophilic replacement of the halogen atom by an azido group, followed by the 1,4-addition of HN3. In the reaction of N-arylsulfonyl-2,6-dihalo-1,4-benzoquinone imines with hydrazoic acid, both halogen atoms are replaced by azido groups, while N-p-tolylsulfonyl-2-methyl-1,4-benzoquinone imine takes up HN3 molecule according to the 1,4-addition pattern.