4-(4-butoxyphenyl)benzyl chloride | 920281-55-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-butoxyphenyl)benzyl chloride
• 英文别名: 4-Butoxy-4'-(chloromethyl)-1,1'-biphenyl；1-butoxy-4-[4-(chloromethyl)phenyl]benzene
• CAS: 920281-55-6
• 化学式: C₁₇H₁₉ClO
• 分子量: 274.79
• InChiKey: UDUOULICEJRIPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(4-羟基苯基)辛烷-1,3-二醇 、 4-(4-butoxyphenyl)benzyl chloride 在 potassium carbonate 、 sodium iodide 作用下， 以 丙酮 为溶剂， 以92%的产率得到1-[4-(4'-butoxybiphenyl-4-ylmethoxy)phenyl]octane-1,3-diol
  参考文献：
  名称：

  Synthesis of new liquid crystalline compounds with side chains containing hydroxy groups or chlorine atom

  摘要：

  Catalytic hydrogenation of the oxo group in 3-hydroxy-1-(4-hydroxyphenyl)octan-1-one gave 1-(4-hydroxyphenyl)octane-1.3-diol and 1-(4-hydroxyphenyl)octan-3-ol which were converted into the corresponding benzyl ethers containing a hydroxy group, 1.3-diol fragment, or chlorine atom in the side chain. The products were shown to possess liquid crystalline properties.

  DOI：

  10.1134/s1070428006030067

文献信息

• Synthesis of new liquid crystalline compounds with side chains containing hydroxy groups or chlorine atom
  作者：V. N. Kovganko、N. N. Kovganko

  DOI：10.1134/s1070428006030067

  日期：2006.3

  Catalytic hydrogenation of the oxo group in 3-hydroxy-1-(4-hydroxyphenyl)octan-1-one gave 1-(4-hydroxyphenyl)octane-1.3-diol and 1-(4-hydroxyphenyl)octan-3-ol which were converted into the corresponding benzyl ethers containing a hydroxy group, 1.3-diol fragment, or chlorine atom in the side chain. The products were shown to possess liquid crystalline properties.