1-phenyl-3-benzyl-3-(dimethylphosphinylmethyl)urea | 841267-34-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-phenyl-3-benzyl-3-(dimethylphosphinylmethyl)urea
• 英文别名: N-Benzyl-N-[(dimethylphosphoryl)methyl]-N'-phenylurea；1-benzyl-1-(dimethylphosphorylmethyl)-3-phenylurea
• CAS: 841267-34-3
• 化学式: C₁₇H₂₁N₂O₂P
• 分子量: 316.34
• InChiKey: NUTMIIGYLXAMIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-benzylaminomethyldimethylphosphine oxide 、 异氰酸苯酯 以 二氯甲烷 为溶剂， 以96%的产率得到1-phenyl-3-benzyl-3-(dimethylphosphinylmethyl)urea
  参考文献：
  名称：

  CARBAMOYL AND THIOCARBAMOYL DERIVATIVES OF N-BENZYL-AMINOMETHYL-DIMETHYL-PHOSPHINE OXIDE

  摘要：

  A series of thirteen new carbampyl and thiocarbampyl derivatives of N-benzyl-aminomethyl-diinethyl-phosphine oxide have been synthesized and characterized. The compounds were prepared via interaction of N-benzyl-aminomethyl-dimethyl-phosphine oxide with the corresponding isocyanates or isothiocyanates. The composition of the synthesized novel compounds was proved by elemental analysis for nitrogen and the structures were confirmed by IR, H-1-, P-31-P-31{H-1} NMR spectroscopy and by mass spectrometry.

  DOI：

  10.1080/10426500490466364

文献信息

• CARBAMOYL AND THIOCARBAMOYL DERIVATIVES OF N-BENZYL-AMINOMETHYL-DIMETHYL-PHOSPHINE OXIDE
  作者：Emil Tashev、Viktoria Lachkova、Helmut Keck、Stoycho Shenkov、Wolfgang Kläui、Sabi Varbanov

  DOI：10.1080/10426500490466364

  日期：2004.9

  A series of thirteen new carbampyl and thiocarbampyl derivatives of N-benzyl-aminomethyl-diinethyl-phosphine oxide have been synthesized and characterized. The compounds were prepared via interaction of N-benzyl-aminomethyl-dimethyl-phosphine oxide with the corresponding isocyanates or isothiocyanates. The composition of the synthesized novel compounds was proved by elemental analysis for nitrogen and the structures were confirmed by IR, H-1-, P-31-P-31H-1} NMR spectroscopy and by mass spectrometry.