4-(Benzylamino)-3-bromopent-3-en-2-one | 664326-10-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(Benzylamino)-3-bromopent-3-en-2-one
• 英文别名: 4-(benzylamino)-3-bromopent-3-en-2-one
• CAS: 664326-10-7
• 化学式: C₁₂H₁₄BrNO
• 分子量: 268.153
• InChiKey: YJFJSGCNWKJCNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-benzylaminopent-3-en-2-one 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 0.33h， 以83%的产率得到4-(Benzylamino)-3-bromopent-3-en-2-one
  参考文献：
  名称：

  Continuous Flow Liquid–Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide

  摘要：

  Incorporating open-source software components (Python, OpenCV), a computer-vision system was used to control the interface level in a gravity-based inline liquid-liquid separation device. This was used in the continuous flow bromination of a series of enaminone substrates. The main byproduct of the reaction, succinimide, was efficiently extracted into the aqueous stream, providing clean products without the need for further purification.

  DOI：

  10.1055/s-0035-1560975

文献信息

• Continuous Flow Liquid–Liquid Separation Using a Computer-Vision Control System: The Bromination of Enaminones with N-Bromosuccinimide
  作者：Matthew O’Brien、Dennis Cooper

  DOI：10.1055/s-0035-1560975

  日期：——

  Incorporating open-source software components (Python, OpenCV), a computer-vision system was used to control the interface level in a gravity-based inline liquid-liquid separation device. This was used in the continuous flow bromination of a series of enaminone substrates. The main byproduct of the reaction, succinimide, was efficiently extracted into the aqueous stream, providing clean products without the need for further purification.