3-氯-5,5-二甲基海因 | 34979-51-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 中文名称: 3-氯-5,5-二甲基海因
• 英文名称: 3-chloro-5,5-dimethyl-imidazolidine-2,4-dione
• 英文别名: 3-Chloro-5,5-dimethyl-2,4-imidazolidinedione；3-Chlor-5,5-dimethyl-hydantoin；3-Chlor-5.5-dimethyl-hydantoin；3-Chloro-5,5-dimethylimidazolidine-2,4-dione
• CAS: 34979-51-6
• 化学式: C₅H₇ClN₂O₂
• 分子量: 162.576
• InChiKey: CNTMIUSYFUFBBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  5,5-二甲基海因 在 次氯酸 作用下， 以 aq. buffer 为溶剂， 生成 3-氯-5,5-二甲基海因
  参考文献：
  名称：

  五元杂环氮化合物的N氯化率

  摘要：

  研究了吡咯烷，吡咯烷酮，琥珀酰亚胺，5,5,5-二甲基恶唑烷-2,4-二酮，5,5-二甲基乙内酰脲和1-羟肟基-5,5-二甲基乙内酰脲与HOCl在水溶液中的N氯化反应动力学。25°C，恒定的离子强度，在宽pH范围内的隔离条件下。本文研究的一组化合物的特征是具有不同的官能团和相同的环状结构，该结构由五元环组成，环中带有氮原子，易被氯化。该系列化合物涵盖九个p K a单元，动力学研究使我们知道，氨基，酰胺或酰亚胺基团的存在会改变含氮化合物的反应性。

  DOI：

  10.1002/poc.3545

文献信息

• Novel Sulfonaminoquinoline Hepcidin Antagonists
  申请人：Buhr Wilm

  公开号：US20120214803A1

  公开（公告）日：2012-08-23

  The present invention relates to novel hepcidin antagonists, pharmaceutical compositions comprising them and the use thereof as medicaments for the use in the treatment of iron metabolism disorders, such as, in particular, iron deficiency diseases and anemias, in particular anemias in connection with chronic inflammatory diseases.

  本发明涉及新型肝铁蛋白拮抗剂，包括它们的药物组合物以及将其用作药物治疗铁代谢紊乱，特别是铁缺乏病和贫血等疾病，特别是与慢性炎症性疾病相关的贫血。
• Microbiological control in aqueous systems
  申请人：——

  公开号：US20030228341A1

  公开（公告）日：2003-12-11

  Biocidally-active 1,3-dibromo-5,5-dialkylhydantoin biocidal compositions in readily identifiable forms are provided in the form of an article of manufacture comprising a packaging material and a biocidal composition contained within said packaging material, wherein said biocidal composition comprises as the biocidally-active component of the biocidal composition (A) at least one 1,3-dibromo-5,5-dialkylhydantoin in which one of the alkyl groups in the 5-position is a methyl group and the other alkyl group in the 5-position contains in the range of 1 to 4 carbon atoms (DBDAH) as the sole biocidally-active ingredient of the composition, or (B) a combination of (i) DBDAH and (ii) at least one non-fluid biocidally-active water treating agent compatible with DBDAH, wherein the weight ratio of (i) to (ii) is in the range of 0.1:0.4 to 99.9:0.1, preferably in the range of 1:1 to 99.9:0.1, more preferably in the range of 9:1 to 99.9:0.1, and most preferably in the range of 19:1 to 99.9:0.1. Each such category of biocidally-active component or components can be, and preferably is in admixture with from 0 to 90 wt % of biocidally-inactive components such as for example one or more binders, fillers, excipients, dyes or colorants, perfumes, stabilizers, and/or manufacturing by-products. The packaging material comprises at least a label suitably identifying the name of the product in the package, and at least a sticker identifying the contents as being an oxidizing agent. The label or another label associated with the packaging material preferably contains other specified information.

  提供了具有生物杀灭活性的1,3-二溴-5,5-二烷基海因醇生物杀灭组合物，其以易于识别的形式呈现为一种制品，包括包装材料和包含在该包装材料中的生物杀灭组合物，其中所述生物杀灭组合物包括作为生物杀灭组合物的生物杀灭活性成分(A)至少一种1,3-二溴-5,5-二烷基海因醇，其中5位的烷基中的一个是甲基，另一个烷基含有1至4个碳原子(DBDAH)作为该组合物的唯一生物杀灭活性成分，或者(B)由(i) DBDAH和(ii)至少一种与DBDAH兼容的非流体生物杀灭水处理剂的组合物组成，其中(i)与(ii)的重量比在0.1:0.4至99.9:0.1的范围内，优选在1:1至99.9:0.1的范围内，更优选在9:1至99.9:0.1的范围内，最优选在19:1至99.9:0.1的范围内。每种生物杀灭活性成分类别或组合物可以与0至90重量％的生物杀灭非活性成分混合，例如一个或多个粘合剂、填充剂、赋形剂、染料或着色剂、香料、稳定剂和/或制造副产品。包装材料至少包括一个标签，适当地标识包装中产品的名称，并且至少包括一个贴纸，标识内容为氧化剂。标签或与包装材料相关的另一个标签最好包含其他指定信息。
• Outdoor films stabilized against chemical attack
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0214507A2

  公开（公告）日：1987-03-18

  A new and improved environmental chemicals resistant light stabilizer package for thermoplastic substrates is disclosed. The stabilizer package comprises a specific oligomeric hindered amine light stabilizer with an ultra-­violet absorber in specified weight ratios. The stabilizer package is useful for stabilizing thermoplastic shaped arti­cles intended for outdoor use in areas where environmental chemicals such as agricultural chemicals, pool chemicals and the like are employed. In a preferred embodiment, a new and improved substantially colorless, light stable greenhouse film is provided which exhibits good weatherability and retention of physical properties even after repeated expo­sure to, for example, pesticides, herbicides and the like.

  本发明公开了一种用于热塑性基材的新型改进型耐环境化学品光稳定剂复合材料。该稳定剂包由特定低聚受阻胺光稳定剂和紫外线吸收剂按特定重量比组成。该稳定剂复合剂适用于在使用农用化学品、泳池化学品等环境化学品的地区稳定用于室外的热塑性成型物品。在一个优选的实施方案中，提供了一种新型和改进的基本无色、光稳定的温室薄膜，即使在反复接触杀虫剂、除草剂等物质后，仍能表现出良好的耐候性和物理性能保持性。
• Method for producing halogenated N-arylpyrazoles
  申请人：Bayer Aktiengesellschaft

  公开号：US11332447B2

  公开（公告）日：2022-05-17

  The present invention relates to a process for preparing compounds of the formula (I) by halogenating compounds of the formula (II), where in R1, R2, R3 and X are defined according to the invention.

  本发明涉及一种制备式 (I) 化合物的工艺 通过卤化式 (II) 的化合物、 其中 R1、R2、R3 和 X 根据本发明定义。
• HALOGEN-RELEASING COMPOSITION FOR LAVATORY CLEANSING
  申请人：Jeyes Group plc

  公开号：EP0817832A1

  公开（公告）日：1998-01-14

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