3-methyl-3,4-dihydro-2,1-benzothiazine 2,2-dioxide | 76653-06-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 3-methyl-3,4-dihydro-2,1-benzothiazine 2,2-dioxide
• 英文别名: 3-methyl-3,4-dihydro-1H-2lambda6,1-benzothiazine 2,2-dioxide；3-methyl-3,4-dihydro-1H-2λ6,1-benzothiazine 2,2-dioxide
• CAS: 76653-06-0
• 化学式: C₉H₁₁NO₂S
• 分子量: 197.258
• InChiKey: VYOJIOQSEBSMEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-苯基-2-丙磺酰基叠氮化物 以 1,1,2-三氯三氟乙烷（CFC-113） 为溶剂， 反应 40.0h， 以24.5%的产率得到3-methyl-3,4-dihydro-2,1-benzothiazine 2,2-dioxide
  参考文献：
  名称：

  The decomposition of .beta.-phenethylsulfonyl azides. Solution chemistry and flash vacuum pyrolysis

  摘要：

  DOI：

  10.1021/ja00396a039

文献信息

• METHODS FOR TREATING SCHIZOPHRENIA
  申请人：Lichter Jay

  公开号：US20120184547A1

  公开（公告）日：2012-07-19

  Provided herein are PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from schizophrenia.

  提供PAK抑制剂。此外，还提供了用于治疗患有精神分裂症的个体的组合物和方法。
• PAK INHIBITORS FOR THE TREATMENT OF CANCER
  申请人：Afraxis, Inc.

  公开号：US20130158043A1

  公开（公告）日：2013-06-20

  Provided herein are methods of utilizing PAK inhibitors for the treatment of cancer. Further provided herein are compounds and formulations utilized for the treatment of cancer.

  本文提供了利用PAK抑制剂治疗癌症的方法。此外，还提供了用于治疗癌症的化合物和配方。
• METHODS FOR TREATING NEUROLOGICAL CONDITIONS
  申请人：Lichter Jay

  公开号：US20130225575A1

  公开（公告）日：2013-08-29

  Provided herein are PAK inhibitors. Also provided herein are compositions and methods for treating an individual suffering from certain neurological conditions.

  本文提供了PAK抑制剂。同时提供了用于治疗患有某些神经疾病的个体的组合物和方法。
• Benzosultams and analogues and their use as fungicides
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：US10736321B2

  公开（公告）日：2020-08-11

  The present disclosure relates to fungicidal active compounds, more specifically to benzosultams and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.

  本公开涉及杀真菌活性化合物，更具体地说，涉及苯并磺胺及其类似物、制备它们的工艺和中间体以及将其用作杀真菌活性化合物，特别是以杀真菌剂组合物的形式使用。本公开还涉及使用这些化合物或包含这些化合物的组合物控制植物的植物病原真菌的方法。
• BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：US20190335753A1

  公开（公告）日：2019-11-07

  The present disclosure relates to fungicidal active compounds, more specifically to benzosultams and analogues thereof, processes and, intermediates for their preparation and use thereof as fungicidal active compound, particularly in the form of fungicide compositions. The present disclosure also relates to methods for the control of phytopathogenic fungi of plants using these compounds or compositions comprising thereof.