2-Methyl-1-methylen-1,2-dihydroisochinolin | 42088-39-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: 2-Methyl-1-methylen-1,2-dihydroisochinolin
• 英文别名: 2-Methyl-1-isochinolonmethid；2-Methyl-1-methylideneisoquinoline
• CAS: 42088-39-1
• 化学式: C₁₁H₁₁N
• 分子量: 157.215
• InChiKey: PSRBLRHACPNTQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• POLYMERIZABLE COMPOUND AND OPTICAL ISOMER
  申请人：DIC Corporation

  公开号：US20180022716A1

  公开（公告）日：2018-01-25

  The present invention provides a polymerizable compound having high storage stability without causing crystal precipitation when added to a polymerizable composition. The present invention also provides a polymerizable composition containing the compound. When the filmy polymer produced through polymerization of the polymerizable composition is irradiated with UV light, it hardly discolors or peels from substrate. Further, the present invention provides a polymer produced through polymerization of the polymerizable composition and an optically anisotropic body using the polymer.

  本发明提供了一种聚合物化合物，具有高储存稳定性，添加到聚合物化合物时不会导致结晶沉淀。本发明还提供了含有该化合物的聚合物化合物。当通过聚合物化合物的聚合产生薄膜状聚合物时，若用紫外光照射，它几乎不会变色或脱落。此外，本发明提供了通过聚合物化合物的聚合产生的聚合物，以及使用该聚合物的光学各向异性体。
• ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR
  申请人：Hirao Ichiro

  公开号：US20120231462A1

  公开（公告）日：2012-09-13

  The present invention provides a double-stranded nucleic acid in which at least one nucleic acid strand includes an unnatural base that forms a self-complementary base pair or an unnatural base that forms a base pair with any natural base with substantially the same thermal stability. The present invention also provides a method of hybridizing a first nucleic acid strand with a second nucleic acid strand, wherein the first nucleic acid strand includes an unnatural base that forms a self-complementary base pair or an unnatural base that forms a base pair with any natural base with substantially the same thermal stability, and a method of applying the nucleic acid to SNP detection, a DNA chip, DNA/RNA computing, or an in vitro translation system. The present invention provides a method of introducing an unnatural base into a nucleic acid strand and thereby controlling the thermodynamic stability in hybridization of the nucleic acid strand.

  本发明提供一种双链核酸，其中至少一个核酸链包括一种不自然碱基，该碱基形成自补碱基对或与任何天然碱基形成具有基本相同热稳定性的碱基对。本发明还提供了一种将第一核酸链与第二核酸链杂交的方法，其中第一核酸链包括一种形成自补碱基对或与任何天然碱基形成具有基本相同热稳定性的不自然碱基，以及将该核酸应用于SNP检测、DNA芯片、DNA/RNA计算或体外翻译系统的方法。本发明提供了一种将不自然碱基引入核酸链中并从而控制核酸链杂交的热力学稳定性的方法。
• ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNALPHA RESPONSES
  申请人：Bristol-Myers Squibb Pharma Company

  公开号：EP3066078B1

  公开（公告）日：2019-05-22
• AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES
  申请人：Bristol-Myers Squibb Company

  公开号：EP3495358B1

  公开（公告）日：2022-04-27
• HETEROBICYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES
  申请人：Bristol-Myers Squibb Company

  公开号：EP3532473B1

  公开（公告）日：2021-09-29