4-hydroxy-5-methoxy-2'-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-biphenyl-3-carbaldehyde | 1134103-83-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-hydroxy-5-methoxy-2'-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-biphenyl-3-carbaldehyde
• 英文别名: 2-Hydroxy-3-methoxy-5-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]benzaldehyde；2-hydroxy-3-methoxy-5-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]benzaldehyde
• CAS: 1134103-83-5
• 化学式: C₂₁H₂₆O₇
• 分子量: 390.433
• InChiKey: YJNPGCWTGZYGID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  28
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  83.4
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  4-benzyloxy-5-methoxy-2'-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-biphenyl-3-carbaldehyde 在 palladium 10% on activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 0.5h， 以96%的产率得到4-hydroxy-5-methoxy-2'-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-biphenyl-3-carbaldehyde
  参考文献：
  名称：

  Effect of the oligo(ethylene glycol) group on the antioxidant activity of manganese salen complexes

  摘要：

  The synthesis and antioxidant activity of oligo( ethylene glycol)-modified manganese salen complexes are reported. Their SOD activities were similar and 2- to 3-fold more potent than the standard compound EUK-134. Their catalase-like activity was lower than that of EUK-134 in the initial conversion rate; however, some analogs exhibited a better catalytic turnover number. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.12.063

文献信息

• Effect of the oligo(ethylene glycol) group on the antioxidant activity of manganese salen complexes
  作者：Wonchoul Park、Dongyeol Lim

  DOI：10.1016/j.bmcl.2008.12.063

  日期：2009.2

  The synthesis and antioxidant activity of oligo( ethylene glycol)-modified manganese salen complexes are reported. Their SOD activities were similar and 2- to 3-fold more potent than the standard compound EUK-134. Their catalase-like activity was lower than that of EUK-134 in the initial conversion rate; however, some analogs exhibited a better catalytic turnover number. (c) 2008 Elsevier Ltd. All rights reserved.