(2S)-2-[2-[(2S)-1-chloro-1-oxo-3-phenylpropan-2-yl]-1,3,5,7-tetraoxopyrrolo[3,4-f]isoindol-6-yl]-3-phenylpropanoyl chloride | 144443-41-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S)-2-[2-[(2S)-1-chloro-1-oxo-3-phenylpropan-2-yl]-1,3,5,7-tetraoxopyrrolo[3,4-f]isoindol-6-yl]-3-phenylpropanoyl chloride
• CAS: 144443-41-4
• 化学式: C₂₈H₁₈Cl₂N₂O₆
• 分子量: 549.367
• InChiKey: MWVUFRAOFAXDNX-VXKWHMMOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  38
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  109
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  N,N-(pyromellitoyl)-bis-L-phenylalanine 在 氯化亚砜 作用下， 生成 (2S)-2-[2-[(2S)-1-chloro-1-oxo-3-phenylpropan-2-yl]-1,3,5,7-tetraoxopyrrolo[3,4-f]isoindol-6-yl]-3-phenylpropanoyl chloride
  参考文献：
  名称：

  Insertion of novel optically active poly(amide-imide) chains containing pyromellitoyl-bis-l-phenylalanine linkages into the nanolayered silicates modified with l-tyrosine through solution intercalation

  摘要：

  In the present investigation, for the first time, functional optically active poly(amide-imide) (PAI)/organonanosilica bionanocomposite films were successfully fabricated through solution intercalation technique. At the start, Cloisite Na+ and protonated form of L-tyrosine amino acid were used for the preparation of the novel chiral organoclay via ion-exchange reaction. Then, PAI containing phenylalanine amino acid was synthesized via solution polycondensation of N,N'-(pyromellitoyl)-bis-phenylalanine diacid chloride (5) with 4,4'-diaminodiphenylsulfone (6). This polymer was end-capped with amine end groups near the completion of the reaction to interact chemically with organoclay. Finally, PAI/organ-nanosilica bionanocomposites films containing 5, 10 and 15% of organoclay were prepared via solution intercalation method through blending of organoclay with the PAI solution. The nanostructures and properties of the PAI/organoclay hybrids were investigated using Fourier transform infrared spectroscopy, X-ray diffraction (XRD), scanning electron microscopy, field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM) and thermogravimetry analysis (TGA) techniques. XRD, FE-SEM and TEM results revealed the formation of exfoliated and intercalated organoclay platelets in the PAI matrix. TGA results indicated that the addition of organoclay into the PAI matrix increases in the thermal decomposition temperatures of the resulted bionanocomposites. The transparency of the nanocomposite films decreased gradually by the addition of organoclay, and the films became semitransparent as well as brittle at high loading of organoclay. Mechanical data indicated improvement in the tensile strength and modulus with organoclay loading. The film containing a 10 wt.%. of organoclay had a tensile strength of the order of 85.24 MPa relative to the 67.52 MPa of the pure PAL (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2011.04.013

文献信息

• Surface Functionalized TiO₂ Nanoparticle Designed for the Preparation of Chiral Poly(amide-imide) Bionanocomposites Containing Phenylalanine Linkage
  作者：Shadpour Mallakpour、Samira Moslemi

  DOI：10.1080/15533174.2013.769005

  日期：2014.2.7

  The surface of titanium dioxide (TiO2) nanoparticles was treated with a silane coupling agent of -aminopropyl-triethoxy silane. An optically active poly(amide-imide) (PAI) was synthesized by the indirect polycondensation reaction of the L-phenylalanine based diacid chloride and 4,4-diaminodiphenylether in the presence of triethylamine in N-methyl-2-pyrrolidone. Then PAI and surface modified TiO2 nanoparticles were used to produce a polymer based bionanocomposites (BNCs) via ultrasonic irradiation process. The obtained BNCs were characterized by means of X-ray diffraction, electron microscopy and thermogravimetric analysis techniques. The results showed that the nanoparticles are homogeneously dispersed in PAI matrix with particle size ranging from 30 to 50 nm.