α-Stearoyl-β-linoleoyl-α'-linolenoin | 102202-98-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: α-Stearoyl-β-linoleoyl-α'-linolenoin
• 英文别名: 1-Stearoyloxy-2-linoleoyloxy-3-α-linolenoyloxy-propan；[2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxy-3-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]oxypropyl] octadecanoate
• CAS: 102202-98-2
• 化学式: C₅₇H₁₀₀O₆
• 分子量: 881.417
• InChiKey: CFIAQJQGPHURGU-VINAAXOKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  21.3
• 重原子数：
  63
• 可旋转键数：
  51
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT AND RELATED PRODUCTS THEREOF
  申请人：Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

  公开号：EP3604269A1

  公开（公告）日：2020-02-05

  The present application relates to extracting, from a traditional Chinese medicine, a plurality of compounds capable of prompting nucleic acid delivery or synthetic compounds, and promoting nucleic acid such as sRNA to absorb and enter a target cell using the extracted compounds or a plurality of combinations and promoting the nucleic acid to enter required target sites in vivo of an object.

  本申请涉及从中药中提取多种能够促使核酸递送的化合物或合成化合物，并利用提取的化合物或多种组合促进核酸（如 sRNA）吸收并进入靶细胞，并促进核酸进入物体体内所需的靶位点。
• EXTRACTION OF PLANT SOURCE "MEDICINAL SOUP" AND MANUAL PREPARATION OF "HERBAL MEDICINE" AND RELATED PRODUCTS
  申请人：Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences

  公开号：EP3789043A1

  公开（公告）日：2021-03-10

  Provided is a preparation method for herbal medicine, comprising the following steps: mixing one or more lipid components and/or with any one or more of the following: nucleic acid, compounds, and macromolecules; and performing heat treatment on the obtained mixture. Also provided is a method for extracting medicinal soup from plants, comprising the following steps: using a solvent to prepare extract solution of a plant; performing differential centrifugation of the extract solution; and using an aqueous solution to re-suspend the precipitate to provide the medicinal soup.

  本发明提供了一种中草药的制备方法，包括以下步骤：将一种或多种脂质成分和/或与以下任一种或多种成分混合：核酸、化合物和大分子；对得到的混合物进行热处理。还提供了一种从植物中提取药汤的方法，包括以下步骤：使用溶剂制备植物提取液；对提取液进行差速离心；以及使用水溶液重新悬浮沉淀，以提供药汤。
• UNSATURATED FATTY ACID ESTER-BASED COMPOSITIONS USEFUL AS PLASTIC ADDITIVES
  申请人：ARKEMA INC.

  公开号：US20160009673A1

  公开（公告）日：2016-01-14

  Compositions useful as plastic additives may be prepared from renewable resources such as vegetable oils by functionalizing an unsaturated fatty acid ester with epoxy, acyloxy, and optionally alkoxy groups.
• APPLICATION OF COMPOUND OR TRADITIONAL CHINESE MEDICINE EXTRACT IN PREPARATION OF NUCLEIC ACID DELIVERY AGENT, AND RELATED PRODUCTS
  申请人：INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICALSCIENCES

  公开号：US20210100905A1

  公开（公告）日：2021-04-08

  The present application relates to extracting a plurality of compounds from a traditional Chinese medicine, or synthesizing a compound capable of promoting nucleic acid delivery, and utilizing the extracted compound, or a plurality of combinations to promote absorption and entry of a nucleic acid such as sRNA into a target cell, and to facilitate the entry of a nucleic acid into a target site in a subject in need thereof
• US9586918B2
  申请人：——

  公开号：US9586918B2

  公开（公告）日：2017-03-07