2-chloro-5-(3,6-dihydro-3-methyl-4-trifluoromethyl-2,6-dioxo-1(2H)pyrimidinyl)benzenesulfonyl chloride | 146436-82-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloro-5-(3,6-dihydro-3-methyl-4-trifluoromethyl-2,6-dioxo-1(2H)pyrimidinyl)benzenesulfonyl chloride
• 英文别名: 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-trifluoromethyl-(2H)-pyrimidin-1-yl]-benzenesulfonyl chloride；2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]benzenesulfonyl chloride
• CAS: 146436-82-0
• 化学式: C₁₂H₇Cl₂F₃N₂O₄S
• 分子量: 403.166
• InChiKey: KFGCPAGILVKFTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  83.1
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-chloro-5-(3,6-dihydro-3-methyl-4-trifluoromethyl-2,6-dioxo-1(2H)pyrimidinyl)benzenesulfonyl chloride 在 氨 作用下， 以 四氢呋喃 为溶剂， 以82.4%的产率得到2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-trifluoromethyl-(2H)-pyrimidin-1-yl]-benzenesulfonamide
  参考文献：
  名称：

  [DE] BENZOLSULFONAMID-DERIVATE ALS HERBIZIDE ODER DESIKKANTE/DEFOLIANTE VERBINDUNGEN
  [EN] BENZENESULPHONAMIDE DERIVATIVES AS HERBICIDES OR DESICCANT/DEFOLIANT COMPOUNDS
  [FR] DERIVES DE BENZOLSULFONAMIDE CONSTITUANT DES COMPOSES HERBICIDES OU DESSICCANTS/DEFOLIANTS

  摘要：

  这项发明涉及公式（I）（I）的苯磺酰胺衍生物，以及它们的制备方法和中间体；以及使用这些化合物或含有这些化合物的制剂来对抗不良植物和使植物脱水/落叶。

  公开号：

  WO2004089914A1

文献信息

• Benzenesulfonamide derivatives and methods for their production
  申请人：Uniroyal Chemical Company, Inc.

  公开号：US05169430A1

  公开（公告）日：1992-12-08

  A compound having the structural formula ##STR1## wherein: R is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, formyl, C.sub.2 -C.sub.6 alkanoyl, C.sub.3 -C.sub.4 alkenyl or C.sub.3 -C.sub.4 alkynyl, or alkali metal; X is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.8 alkoxy, cyano, or halogen; Y is hydrogen, halogen, or C.sub.1 -C.sub.4 dialkylamino; R.sup.1 is hydrogen, C.sub.1 -C.sub.8 straight chain or branched alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 alkoxy or C.sub.3 -C.sub.8 hydroxyalkyl; R.sup.2 is hydrogen, C.sub.1 -C.sub.8 straight chain or branched alkyl, C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, halo substituted C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.1 -C.sub.4 alkoxy, hydroxy C.sub.1 -C.sub.4 alkyl, cyano C.sub.1 -C.sub.4 alkyl, 2,3-epoxypropyl, 2,2-dialkoxyethyl, alkoxyalkyl, phenyl, aralkyl, C.sub.1 -C.sub.4 acyl, C.sub.1 -C.sub.4 carbalkoxyalkyl, C.sub.1 -C.sub.4 carbalkoxyalkyl substituted by C.sub.1 -C.sub.4 alkyl, phenylmethyl or methylthioethyl, (1,3-dioxolan-2-yl)alkyl, dialkylaminoethyl, or tetrahydrofuranylmethyl; R.sup.3 is hydrogen, halogen or C.sub.1 -C.sub.4 alkyl; R.sup.4 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 haloalkyl; R.sup.1 and R.sup.2 taken together form a C.sub.3 -C.sub.8 membered heterocyclic ring containing one or more heteroatoms. In addition, processes and novel intermediate compounds that are useful for making the compound are set forth. A method for controlling weeds which comprises applying a herbicidally effective amount of the compound recited above is described. Also disclosed is a composition useful as an herbicide which includes a compound of this invention and a suitable carrier therefor.

  一种化合物具有结构式##STR1##其中：R是氢，C.sub.1-C.sub.4烷基，C.sub.1-C.sub.4卤代烷基，甲酰基，C.sub.2-C.sub.6烷酰基，C.sub.3-C.sub.4烯基或C.sub.3-C.sub.4炔基，或碱金属；X是C.sub.1-C.sub.4烷基，C.sub.1-C.sub.8烷氧基，氰基或卤素；Y是氢，卤素或C.sub.1-C.sub.4双烷基氨基；R.sup.1是氢，C.sub.1-C.sub.8直链或支链烷基，C.sub.3-C.sub.8环烷基，C.sub.3-C.sub.8烯基，C.sub.3-C.sub.8烷氧基或C.sub.3-C.sub.8羟基烷基；R.sup.2是氢，C.sub.1-C.sub.8直链或支链烷基，C.sub.3-C.sub.8烯基，C.sub.3-C.sub.8环烷基，卤代C.sub.3-C.sub.8烯基，C.sub.3-C.sub.8炔基，C.sub.1-C.sub.4烷氧基，羟基C.sub.1-C.sub.4烷基，氰基C.sub.1-C.sub.4烷基，2,3-环氧丙基，2,2-二烷氧基乙基，烷氧基烷基，苯基，芳基烷基，C.sub.1-C.sub.4酰基，C.sub.1-C.sub.4羧基烷氧基烷基，被C.sub.1-C.sub.4烷基取代的C.sub.1-C.sub.4羧基烷氧基烷基，苯基甲基或甲硫乙基，（1,3-二氧杂环戊烷-2-基）烷基，双烷基氨基乙基或四氢呋喃基甲基；R.sup.3是氢，卤素或C.sub.1-C.sub.4烷基；R.sup.4是C.sub.1-C.sub.4烷基或C.sub.1-C.sub.4卤代烷基；R.sup.1和R.sup.2共同形成一个含有一个或多个杂原子的C.sub.3-C.sub.8环的杂环。此外，还提供了制备该化合物有用的过程和新的中间体化合物。还描述了一种控制杂草的方法，该方法包括施用上述化合物的除草有效量。还揭示了一种用作除草剂的组合物，其中包括本发明的化合物和适当的载体。
• Pyrimidylbensulfonyl chloride compounds
  申请人：Uniroyal Chemical Company, Inc.

  公开号：US05486610A1

  公开（公告）日：1996-01-23

  Pyrimidinylbenzenesulfonyl chloride compounds of the formula ##STR1## wherein R is hydrogen, C.sub.1 -C.sub.4 alkyl, or C.sub.1 -C.sub.4 haloalkyl; X is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.8 alkoxy, or halogen; Y is hydrogen or halogen; R.sup.3 is hydrogen, halogen or C.sub.1 -C.sub.4 alkyl; and R.sup.4 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 haloalkyl. The compounds are useful as intermediates in the preparation of herbicides.

  该化合物的化学式为##STR1##其中R为氢，C.sub.1-C.sub.4烷基或C.sub.1-C.sub.4卤代烷基; X为C.sub.1-C.sub.4烷基，C.sub.1-C.sub.8烷氧基或卤素; Y为氢或卤素; R.sup.3为氢，卤素或C.sub.1-C.sub.4烷基; R.sup.4为C.sub.1-C.sub.4烷基或C.sub.1-C.sub.4卤代烷基。这些化合物可用作除草剂制备中间体。
• Intermediate isocyana to benzenesulfonamide compounds
  申请人：Uniroyal Chemical Company, Inc.

  公开号：US05324854A1

  公开（公告）日：1994-06-28

  Compounds having the formula: ##STR1## wherein X is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.8 alkoxy or halogen; Y is hydrogen, halogen, or C.sub.1 -C.sub.4 dialkylamino; R.sup.1 is C.sub.1 -C.sub.8 straight chain or branched alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 alkenyl or C.sub.3 -C.sub.8 alkoxy; R.sup.2 is C.sub.1 -C.sub.8 straight chain or branched alkyl, C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 cycloalkyl, halo substituted C.sub.3 -C.sub.8 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.1 -C.sub.4 alkoxy, cyano C.sub.1 -C.sub.4 alkyl, alkoxyalkyl, phenyl, aralkyl, C.sub.1 -C.sub.4 acyl, C.sub.1 -C.sub.4 carbalkoxyalkyl, C.sub.1 -C.sub.4 carbalkoxyalkyl substituted by C.sub.1 -C.sub.4 alkyl, phenylmethyl or methylthioethyl, dialkylaminoethyl, or tetrahydrofuranylmethyl; R.sup.1 and R.sup.2 taken together form a C.sub.3 -C.sub.8 membered heterocyclic ring containing one or more heteroatoms. The compounds are useful as intermediates for making herbicides.

  具有以下式子的化合物：##STR1## 其中X为C.sub.1-C.sub.4烷基，C.sub.1-C.sub.8烷氧基或卤素；Y为氢，卤素或C.sub.1-C.sub.4双烷基氨基；R.sup.1为C.sub.1-C.sub.8直链或支链烷基，C.sub.3-C.sub.8环烷基，C.sub.3-C.sub.8烯基或C.sub.3-C.sub.8烷氧基；R.sup.2为C.sub.1-C.sub.8直链或支链烷基，C.sub.3-C.sub.8烯基，C.sub.3-C.sub.8环烷基，卤素取代的C.sub.3-C.sub.8烯基，C.sub.3-C.sub.8炔基，C.sub.1-C.sub.4烷氧基，氰基C.sub.1-C.sub.4烷基，烷氧基烷基，苯基，芳基烷基，C.sub.1-C.sub.4酰基，C.sub.1-C.sub.4碳基氧烷基，C.sub.1-C.sub.4碳基氧烷基，其被C.sub.1-C.sub.4烷基取代，苯甲基或甲硫基乙基，双烷基氨基乙基或四氢呋喃基甲基；R.sup.1和R.sup.2结合形成一个含有一个或多个杂原子的C.sub.3-C.sub.8环的杂环。这些化合物可用作制造除草剂的中间体。
• Benzenesulphonamide derivatives as herbicides or desiccant/defoliant compounds
  申请人：Hamprecht Gerhard

  公开号：US20060211577A1

  公开（公告）日：2006-09-21

  The present invention relates to benzenesulfonamide derivatives of the formula I in which the variables are as defined below: X 1 is hydrogen or halogen; X 2 is hydrogen, cyano, CS—NH 2 , halogen, alkyl or haloalkyl; X 3 is hydrogen, cyano, alkyl, alkoxyalkyl, cycloalkyl, alkenyl, alkynyl or phenylalkyl, where the phenyl radical for its part may be substituted; Y is a group —C(A)B, SO 2 or SO 2 NR 2 ; A is oxygen or sulfur; B is oxygen, sulfur, NR 2 or a bond; R 1 is hydrogen, halogen, hydroxy, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, cycloalkenyl, alkynyl, alkoxy, cycloalkyloxy, alkenyloxy, alkynyloxy, aryl, aryloxy, arylalkyl, where the 13 last mentioned radicals for their part may be substituted; unsubstituted or substituted four- to six-membered heterocyclyl; unsubstituted or substituted four- to six-membered heterocyclyl-C 1 -C 4 -alkyl; unsubstituted or substituted five- or six-membered heteroaryl having one to four nitrogen atoms or having one to three nitrogen atoms and one oxygen or one sulfur atom or having one oxygen or sulfur atom; or unsubstituted or substituted five- or six-membered heteroaryl-C 1 -C 4 -alkyl having one to four nitrogen atoms or having one to three nitrogen atoms and one oxygen or one sulfur atom or having one oxygen or sulfur atom; R 2 is hydrogen,-alkyl, alkenyl, alkynyl, cycloalkyl, where the four last mentioned radicals may be partially or fully halogenated; or R 1 and R 2 together with the nitrogen atom to which they are attached form an unsubstituted or substituted three- to seven-membered heterocycle; Q is a radical from the group consisting of Q 1 to Q 39 ; to processes and intermediates for their preparation and to the use of these compounds or of the compositions comprising these compounds for controlling unwanted plants and for the desiccation/defoliation of plants.

  本发明涉及公式I的苯磺酰胺衍生物，其中变量定义如下：X1为氢或卤素；X2为氢、氰、CS—NH2、卤素、烷基或卤代烷基；X3为氢、氰、烷基、烷氧基烷基、环烷基、烯基、炔基或苯基烷基，其中苯基基团本身可以被取代；Y为—C(A)B、SO2或SO2NR2基团；A为氧或硫；B为氧、硫、NR2或键；R1为氢、卤素、羟基、烷基、环烷基烷基、烯基、环烯基、炔基、烷氧基、环烷氧基、烯氧基、炔氧基、芳基、芳氧基、芳基烷基，其中最后提到的基团本身可以被取代；未取代或取代的四至六元杂环基；未取代或取代的四至六元杂环基-C1-C4-烷基；未取代或取代的具有一到四个氮原子或具有一到三个氮原子和一个氧或硫原子或具有一个氧或硫原子的五元或六元杂芳基；或未取代或取代的具有一到四个氮原子或具有一到三个氮原子和一个氧或硫原子或具有一个氧或硫原子的五元或六元杂芳基-C1-C4-烷基；R2为氢、烷基、烯基、炔基、环烷基，其中最后提到的基团可能部分或完全卤代；或R1和R2与它们连接的氮原子一起形成未取代或取代的三至七元杂环；Q为来自由Q1到Q39组成的基团；以及它们的制备过程和中间体，以及使用这些化合物或包含这些化合物的组合物来控制不良植物和进行植物脱水/脱叶。
• BENZENESULFONAMIDE DERIVATIVES AS HERBICIDES
  申请人：UNIROYAL CHEMICAL COMPANY, Inc.

  公开号：EP0598774A1

  公开（公告）日：1994-06-01