phthalic acid ; sulfate | 109219-22-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phthalic acid ; sulfate
• 英文别名: Phthalsaeure; Sulfat；Phthalic acid;sulfuric acid
• CAS: 109219-22-9
• 化学式: C₈H₆O₄*H₂O₄S
• 分子量: 264.213
• InChiKey: FSDZFXDDKLLPRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.43
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  158
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  邻苯二甲酸 在 硫酸 作用下， 生成 phthalic acid ; sulfate
  参考文献：
  名称：

  Hoogewerff; van Dorp, Recueil des Travaux Chimiques des Pays-Bas, 1902, vol. 21, p. 353

  摘要：

  DOI：

文献信息

• Method for inactivating pathogens
  申请人：——

  公开号：US20020102230A1

  公开（公告）日：2002-08-01

  A method for inactivating pathogens is provided. This method generally comprises the application of an effective amount of inhibitory compounds, preferably as a topical formulation, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The inhibitory compounds include a copolymer of maleic acid and styrenesulfonic acid, polyvinyl phthalate sulphate, and their salts. The method can be used for preventing transmission and infection of sexual transmitted diseases, for treating and preventing bacterial vaginitis, and as a contraceptive method. These contraceptives generally have fewer side effects than conventional vaginal contraceptives (e.g., Nonoxynol-9). For example, the compounds useful in the methods of the invention not only are not toxic to natural and beneficial flora and, thus, do not upset the local microbiological balance, but also help maintain a low pH in the vaginal environment.

  本文提供了一种灭活病原体的方法。这种方法一般包括施用有效量的抑制性化合物，最好是外用制剂，可以单独施用，也可以与药学上可接受的载体或稀释剂结合施用。抑制性化合物包括马来酸和苯乙烯磺酸的共聚物、聚邻苯二甲酸乙烯酯硫酸盐及其盐类。该方法可用于预防性传播疾病的传播和感染，治疗和预防细菌性阴道炎，也可用作避孕方法。与传统的阴道避孕药（如壬苯醇-9）相比，这些避孕药的副作用一般较小。例如，本发明方法中使用的化合物不仅对天然有益菌群没有毒性，因此不会破坏当地的微生物平衡，而且还有助于维持阴道环境的低 pH 值。
• METHODS AND REAGENTS FOR VIRUS ISOLATION AND DETECTION
  申请人：Li Xing-Xiang

  公开号：US20100297604A1

  公开（公告）日：2010-11-25

  The present invention relates to reagents and methods used in virus isolation and analysis.
• Methods to detect and treat diseases
  申请人：Wang Tianxin

  公开号：US20130131423A1

  公开（公告）日：2013-05-23

  The current invention discloses methods to treat disease caused by virus infection, bacterial infection, parasites infection, autoimmune disease, disease caused by production of unwanted antibodies, sepsis as well as methods to treat cancer and methods for virus infection detection using blood purification method. The current invention provides a method to treat pathogen infection by inactivating the pathogens in the blood. During the treatment, blood is withdrawn from a patient and is separated into its plasma and cellular components. The plasma portion is treated with physical means such as UV radiation to inactivate the pathogens inside and then is returned to the patient. The current invention also provide a method to treat cancer especially to prevent tumor metastasis and tumor recurrence by removing and/or inactivating (e.g. killing) the circulating tumor cells (CTC) in the blood after removing the tumor or treating the tumor with therapeutical means.
• US6043293A
  申请人：——

  公开号：US6043293A

  公开（公告）日：2000-03-28
• [EN] METHOD FOR INACTIVATING PATHOGENS<br/>[FR] METHODE D'INACTIVATION D'AGENTS PATHOGENES
  申请人：QUEST MEDICINE INC

  公开号：WO2002045706A2

  公开（公告）日：2002-06-13

  A method for inactivating pathogens is provided. This method generally comprises the application of an effective amount of inhibitory compounds, preferably as a topical formulation, either alone or in combination with a pharmaceutically acceptable carrier or diluent. The inhibitory compounds include a copolymer of maleic acid and styrenesulfonic acid, polyvinyl phthalate sulphate, and their salts. The method can be used for preventing transmission and infection of sexual transmitted diseases, for treating and preventing bacterial vaginitis, and as a contraceptive method. These contraceptives generally have fewer side effects than conventional vaginal contraceptives (e.g., Nonoxynol-9). For example, the compounds useful in the methods of the invention not only are not toxic to natural and beneficial flora and, thus, do not upset the local microbiological balance, but also help maintain a low pH in the vaginal environment.