3-formyl-9H-hexylcarbazole | 1431855-58-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-formyl-9H-hexylcarbazole
• 英文别名: 2-[(9-Hexylcarbazol-3-yl)methylideneamino]-4-nitrophenol
• CAS: 1431855-58-1
• 化学式: C₂₅H₂₅N₃O₃
• 分子量: 415.492
• InChiKey: GRHNFGMMCNQJHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  83.3
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-hexylcarbazole 在 三氯氧磷 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 20.5h， 生成 3-formyl-9H-hexylcarbazole
  参考文献：
  名称：

  A new carbazole-based Schiff-base as fluorescent chemosensor for selective detection of Fe3+ and Cu2+

  摘要：

  A new carbazole-based Schiff-base (I) as a multi-functional fluorescent chemosensor was designed, synthesized and characterized, which can selectively recognized Fe3+ and Cu2+ ions over a number of other metal ions. Compound I could detect Fe3+ and Cu2+ by UV-Vis method and fluorescence method. The stoichiometry ratio of 1-Fe3+ and 1-Cu2+ are 2:1 and 1:1, respectively, by the method of Job's plot. Moreover, the detection limits were calculated to be 4.23 x 10(-6) mol/L for Fe3+ ion and 5.67 x 10(-6) mol/L for Cu2+ ion. In the presence of Fe3+/Cu2+ ions, the fluorescence enhancement was attributed to the inhibited C=N isomerization and the obstructed excited state intramolecular proton transfer (ESIPT) of compound 1. At the same time, the interactions of compounds 1 with other ions were also investigated and unobvious UV-Vis absorption and fluorescence spectral changes were observed. Thus a new kind of chemosensor for Fe3+/Cu2+ with high sensitivity and selectivity was introduced. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2013.02.043