2-[2-[2-[Bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethoxy]ethoxycarbonyl-[2-(4-nitrophenoxy)carbonyloxyethyl]amino]ethyl (4-nitrophenyl) carbonate | 252378-65-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-[2-[Bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethoxy]ethoxycarbonyl-[2-(4-nitrophenoxy)carbonyloxyethyl]amino]ethyl (4-nitrophenyl) carbonate
• CAS: 252378-65-7
• 化学式: C₄₂H₄₀N₆O₂₅
• 分子量: 1028.8
• InChiKey: FRAPEMMXJFOGHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  73
• 可旋转键数：
  32
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  394
• 氢给体数：
  0
• 氢受体数：
  25

反应信息

• 作为反应物：
  描述：

  二乙醇胺 、 2-[2-[2-[Bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethoxy]ethoxycarbonyl-[2-(4-nitrophenoxy)carbonyloxyethyl]amino]ethyl (4-nitrophenyl) carbonate 在 吡啶 作用下， 反应 5.0h， 生成 Bis-(2-hydroxy-ethyl)-carbamic acid 2-({2-[2-(bis-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-carbamoyloxy)-ethoxy]-ethoxycarbonyl}-{2-[bis-(2-hydroxy-ethyl)-carbamoyloxy]-ethyl}-amino)-ethyl ester
  参考文献：
  名称：

  Synthesis of multivalent carbonate esters by divergent growth of branched carbamates

  摘要：

  Multivalent 4-nitrophenyl (PNP)-carbonate esters were prepared from carbonate ester-containing core groups by a new divergent-growth process. The process doubles the number of PNP-carbonate esters with each round of growth, or branching, which occurs by reacting an N,N-dihydroxylalkyl amine with a PNP-carbonate ester. The resulting N,N-dihydroxyalkyl carbamate contains two hydroxyl groups for each original PNP-carbonate ester. The hydroxyl groups are converted in situ to PNP-carbonate esters, and the process can be repeated to provide successive generations of dendrimer-like branched structures of increased valence. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(01)00078-8
• 作为产物：
  描述：

  Bis(4-nitrophenyl) (oxybis(ethane-2,1-diyl)) bis(carbonate) 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 25.0h， 生成 2-[2-[2-[Bis[2-(4-nitrophenoxy)carbonyloxyethyl]carbamoyloxy]ethoxy]ethoxycarbonyl-[2-(4-nitrophenoxy)carbonyloxyethyl]amino]ethyl (4-nitrophenyl) carbonate
  参考文献：
  名称：

  Synthesis of multivalent carbonate esters by divergent growth of branched carbamates

  摘要：

  Multivalent 4-nitrophenyl (PNP)-carbonate esters were prepared from carbonate ester-containing core groups by a new divergent-growth process. The process doubles the number of PNP-carbonate esters with each round of growth, or branching, which occurs by reacting an N,N-dihydroxylalkyl amine with a PNP-carbonate ester. The resulting N,N-dihydroxyalkyl carbamate contains two hydroxyl groups for each original PNP-carbonate ester. The hydroxyl groups are converted in situ to PNP-carbonate esters, and the process can be repeated to provide successive generations of dendrimer-like branched structures of increased valence. (C) 2001 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(01)00078-8