5-Azaindazole compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
5-Azaindazole compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Potassium cation is introduced into the (P4Mo6} systems, leading to 18-connected assemblies, which represents the highest connection of the POMs and shows bifunctional electrocatalytic activities and excellent photocatalytic activities.
Dense homogeneous textile composed from continuous bead-free sodium potassium niobate (NKN) nanofibers 100 μm long and 50-200 nm in diameter was sintered by sol-gel calcination assisted electrospinning. High resolution electron microscopy and x-ray diffraction revealed preferential cube-on-cube growth of fibers in [001] direction. Raman spectrum of NKN fibers contains all the features characteristic
Transparent and Luminescent Thin Films of Partially Substituted La[sub 10](SiO[sub 4])[sub 6]O[sub 3]:Eu[sup 3+] Apatite-Type Silicates
作者:Yuichi Otsuka、Shinobu Fujihara
DOI:10.1149/1.2768303
日期:——
Partially substituted oxyapatite silicates, La 8 M 2 (SiO4 ) 6 O 3 :Eu 3+ (M = Na, K, Mg, Ca, Sr, Y, and Gd), were prepared as powders and thin films by the conventional solid-state reaction and the sol-gel method, respectively. X-ray diffractometry and Fourier transform infrared spectroscopy were used to evaluate crystallinity and structure of the silicates. Transparent thin-film samples fabricated
部分取代的氧磷灰石硅酸盐 La 8 M 2 (SiO 4 ) 6 O 3 :Eu 3+ (M = Na、K、Mg、Ca、Sr、Y 和 Gd),通过常规固体制备为粉末和薄膜态反应和溶胶-凝胶法,分别。X 射线衍射法和傅里叶变换红外光谱用于评估硅酸盐的结晶度和结构。在石英玻璃基板上制造的透明薄膜样品在紫外光照射下通过从 O 2- 到 Eu 3+ 的电荷转移激发,由于 Eu 3+ 表现出强烈的红色发射。未取代硅酸盐的激发波长为 268 nm,因主体硅酸盐中的取代而发生偏移。这种转变可以通过晶格常数 c 的变化以及相应的 Eu-O 距离的变化来解释。