o-(IPhMe2AsCH2)C6H4NC | 760999-70-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: o-(IPhMe2AsCH2)C6H4NC
• 英文别名: (2-isocyanophenyl)methyl-dimethyl-phenylarsanium;iodide
• CAS: 760999-70-0
• 化学式: C₁₆H₁₇AsN*I
• 分子量: 425.144
• InChiKey: JNRZBGZWPRBKHL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.94
• 重原子数：
  19.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  4.36
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  氟硼酸钠 、 cis-dichlorobis(triphenylphosphine)platinum(II) 、 o-(IPhMe2AsCH2)C6H4NC 以 丙酮 为溶剂， 生成 trans-[PtClI(CNC6H4CH2AsMe2Ph)(PPh3)2](BF4)
  参考文献：
  名称：

  Synthesis and cyclization reactions of platinum(II)-coordinated arsonium-substituted phenyl isocyanides, o-(I−R3As+–CH2)C6H4N≡C

  摘要：

  The arsonium-substituted isocyanides, o-(I- +R3AsCH2)C(6)H(4)NdropC (AsR3 = AsPh3, L-1; AsMePh2, L-2; AsMe2Ph, L-3), were prepared by reaction of o-(chloromethyl)phenyl isocyanide, o-(CH2Cl)C(6)H(4)NdropC, with a slight molar stoichiometric amount of the arsine in the presence of a Mold excess of NaI in acetone at room temperature. The isocyanides L-1-L-3 coordinate to some Pt(II) complexes such as trans-[PtX{o-(I- +R3AsCH2)C6H4NC}(PPh3)(2)] [BF4] (AsR3 = AsPh3, 1; AsMePh2, 2; AsMe2Ph, 3; X = Cl, I) and [PtX {o-(I- +R3AsCH2)C6H4NC}(Ph2PCH=CHPPh2)] [BF4] (AsR3 = AsMePh2, 4; X = Cl, I). Complexes 2-4 are converted in CH2Cl2 at room temperature in the presence of NEt3 to the corresponding indolidin-2-ylidene derivatives trans-[PtX{CN(H)-o-C6H4C(AsR3)}(PPh3)(2)]BF4] (AsR3 =AsPh3, 5; AsMePh2, 6; AsMe2Ph, 7) and [PtX{CN(H)-o-C6H4(AsMePh2)}(Ph2PCH=CHPPh2)][BF4] (8). (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2004.02.035