2,3-Dihydro-benzo[4,5]imidazo[2,1-b]oxazole | 61532-57-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 2,3-Dihydro-benzo[4,5]imidazo[2,1-b]oxazole
• 英文别名: 1,3-Oxazolidino[2,3-b]benzimidazole；1,2-dihydro-[1,3]oxazolo[3,2-a]benzimidazole
• CAS: 61532-57-8
• 化学式: C₉H₈N₂O
• 分子量: 160.175
• InChiKey: CVOZYUMUHHAGFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  27
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 4-substituted or unsubtituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid derivatives as beta-lactamase inhibitors
  申请人：Mansour Suhayl Tarek

  公开号：US20070232582A1

  公开（公告）日：2007-10-04

  The present invention relates to novel, low molecular weight broad spectrum compounds in particular to a class of 4-substituted or unsubstituted-7-hydro-1,4-thiazepine-7-[bicyclic or tricyclic heteroaryl] substituted-3,6-dicarboxylic acid or their derivatives which have β-lactamase inhibitory and antibacterial properties. The compounds are therefore useful in the treatment of antibacterial infections in humans or animals, either alone or in combination with other antibiotics.