[Pt(1-methylcytosine-N3)3I]I | 880148-76-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: [Pt(1-methylcytosine-N3)3I]I
• CAS: 880148-76-5
• 化学式: C₁₅H₂₁IN₉O₃Pt*I
• 分子量: 824.279
• InChiKey: ZVVMEPYIBULYOG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  [Pt(1-methylcytosine)3Cl]NO3 * 1.5 H2O 、 potassium iodide 以 水 为溶剂， 以80%的产率得到[Pt(1-methylcytosine-N3)3I]I
  参考文献：
  名称：

  Coexistence of major and minor tautomers of 1-methylcytosine (1-MeC) in a single metal complex, trans-Pt(1-MeC-N3)(1-MeC-N4)X2 (X=Cl, I): metal migration N3→N4 at acidic pH

  摘要：

  Two complexes of composition trans-Pt(1-MeC-N3)(1-MeC-N4)I-2 . 2H(2)O (4) and trans-Pt(1-MeC-N3)(1-MeC-N4)Cl-2 (5) are described and characterized by X-ray analysis, which simultaneously contain the preferred aminooxo tautomer I and the rare iminooxo tautomer II of 1-methyleytosine (1-MeC) bonded to the heavy metal, via N3 and N4, respectively. Formation of 4 originates from [Pt(1-MeC-N3)(3)I]I (2), which likewise has been characterized by X-ray crystal structure analysis. A feasible way of formation of 4, which involves a metal migration process from N3 to N4 occurring at moderately acidic pH, is proposed. It appears to be yet another mechanism of metal migration, different from previously established cases which are redox-assisted and hydroxide-promoted, respectively. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2004.07.009