3-chloro-5-(4-chlorophenyl)-4-(3-chloro-5-methoxy-2-pyridyl)-6-methylpyridazine | 940933-10-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 3-chloro-5-(4-chlorophenyl)-4-(3-chloro-5-methoxy-2-pyridyl)-6-methylpyridazine
• 英文别名: 3-chloro-4-(3-chloro-5-methoxypyridin-2-yl)-5-(4-chlorophenyl)-6-methylpyridazine
• CAS: 940933-10-8
• 化学式: C₁₇H₁₂Cl₃N₃O
• 分子量: 380.661
• InChiKey: ODQBETIQLGVEEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  47.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5-(4-chlorophenyl)-4-(3-chloro-5-methoxy-2-pyridyl)-6-methyl-2H-pyridazin-3-one 在 三氯氧磷 、 水 、 碳酸氢钠 作用下， 以 乙酸乙酯 为溶剂， 反应 2.08h， 生成 3-chloro-5-(4-chlorophenyl)-4-(3-chloro-5-methoxy-2-pyridyl)-6-methylpyridazine
  参考文献：
  名称：

  PYRIDAZINE COMPOUND AND USE THEREOF

  摘要：

  公开号：

  EP1958946B1

文献信息

• [EN] NOVEL IMIDAZOLE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS D'IMIDAZOLE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2009053102A1

  公开（公告）日：2009-04-30

  The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; R5 is halogen; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.

  本发明涉及式（I）的新型咪唑衍生物作为活性成分，具有微生物杀灭活性，特别是杀真菌活性：其中R1是卤素，C1-C4烷基或C1-C4卤代烷基；R2是可选取代的芳基或杂环芳基；R3是卤素；R4是氢，卤素，C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，C1-C4卤代烷氧基或氰基；R5是卤素；X是N或C（R）；R是氢，卤素，C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，C1-C4卤代烷氧基或氰基；或其农药可用盐形式；但当X为C（R）时，R2不能是可选取代的芳基。
• [EN] PYRIDAZINE FUNGICIDES<br/>[FR] FUNGICIDES À BASE DE PYRIDAZINE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2009090039A1

  公开（公告）日：2009-07-23

  The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is methyl, ethyl or isopropyl; R2 is chloro, fluoro, hydroxy or C1-C2alkoxy; R3 is H, chloro, fluoro, methoxy or C1-C3alkyl; R4 is chloro, fluoro or bromo; and R5 is H, fluoro or methoxy; or an agrochemically usable salt form thereof; with the proviso that when R1 is methyl, R2 is chloro and R3 is H, then R4 or R5 is different from fluoro.

  本发明涉及一种新型吡嗪衍生物，其化学式为（I），作为活性成分具有微生物杀菌活性，特别是真菌杀菌活性：其中R1为甲基、乙基或异丙基；R2为氯、氟、羟基或C1-C2烷氧基；R3为H、氯、氟、甲氧基或C1-C3烷基；R4为氯、氟或溴；R5为H、氟或甲氧基；或其农药可用盐形式；但当R1为甲基，R2为氯，R3为H时，R4或R5不为氟。
• [EN] PYRIDAZINE DERIVATIVES USEFUL AS FUNGICIDES AND FOR THE TREATMENT OF CANCER<br/>[FR] DÉRIVÉS DE PYRIDAZINE UTILES EN TANT QUE FONGICIDES ET POUR LE TRAITEMENT DU CANCER
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2009080314A1

  公开（公告）日：2009-07-02

  The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: formula (I) wherein R1 is C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl; R2 is hydrogen or an optionally substituted alkyl, aryl or heteroaryl; R3 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; R4 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; or R3 and R4 together can be part of a carbocyclic or heterocyclic 3- to 8-membered ring; R5 is optionally substituted aryl or heteroaryl; and R6 is hydroxy, halogen, C1-C6alkoxy, C1-C6haloalkoxy, C1-C6alkylthio or C1-C6haloalkylthio; or an agrochemically usable salt form thereof.

  本发明涉及式（I）的新型吡嗪衍生物，其作为活性成分具有微生物杀菌活性，特别是杀真菌活性：式（I）其中，R1是C1-C6烷基，C1-C6卤代烷基或C3-C6环烷基；R2是氢或可选取代的烷基，芳基或杂环芳基；R3是氢，C1-C6烷基或C1-C6卤代烷基；R4是氢，C1-C6烷基或C1-C6卤代烷基；或R3和R4可以成为碳环或杂环3-8元环的一部分；R5是可选取代的芳基或杂环芳基；R6是羟基，卤素，C1-C6烷氧基，C1-C6卤代烷氧基，C1-C6烷基硫醚或C1-C6卤代烷基硫醚；或其农药可用盐形式。
• [EN] NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES<br/>[FR] NOUVEAUX DÉRIVÉS DE 5-(PYRIDIN-3-YL)-PYRIDAZINE ET LEUR UTILISATION EN TANT QUE MICROBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2011076501A1

  公开（公告）日：2011-06-30

  The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity.

  本发明涉及一种新的吡啶嗪衍生物，其化学式为（I），作为活性成分具有微生物杀菌活性，特别是具有杀真菌活性。
• PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES
  申请人：Lamberth Clemens

  公开号：US20100022526A1

  公开（公告）日：2010-01-28

  The present invention relates to compounds of formula (I) wherein R 1 , R 2 , R 3 and R 4 are as defined in claim 1, which are useful as fungicides.

  本发明涉及式（I）中的化合物，其中R1，R2，R3和R4如权利要求1所定义，其作为杀真菌剂有用。