4'-(6-Bromo-pyren-1-ylethynyl)-[2,2';6',2'']terpyridine | 479621-48-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 4'-(6-Bromo-pyren-1-ylethynyl)-[2,2';6',2'']terpyridine
• 英文别名: 4-[2-(6-Bromopyren-1-yl)ethynyl]-2,6-dipyridin-2-ylpyridine
• CAS: 479621-48-2
• 化学式: C₃₃H₁₈BrN₃
• 分子量: 536.43
• InChiKey: UHADWHUZYZOOQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  37
• 可旋转键数：
  4
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-乙炔基-2-吡啶-2-基吡啶 、 4'-(6-Bromo-pyren-1-ylethynyl)-[2,2';6',2'']terpyridine 在 四(三苯基膦)钯 、 二异丙胺 作用下， 以 苯 为溶剂， 以90%的产率得到4'-(6-[2,2']Bipyridinyl-5-ylethynyl-pyren-1-ylethynyl)-[2,2';6',2'']terpyridine
  参考文献：
  名称：

  Stepwise construction of pyrene bridged polytopic ligands carrying acetylenic tethers

  摘要：

  Reliable and practical synthetic routes for the construction of. polytopic bipyridine or terpyridine frameworks are presented. These ligands are prepared by sequential Pd-promoted cross-coupling reactions between selected ethynyl substituted bipyridine or terpyridine building blocks and 1,6-dibromopyrene. A convergent synthetic route for the preparation of Ru complexes bearing peripheral uncomplexed fragments has been established starting from preorganized building blocks carrying a bromide function. This protocol highlights the use of metallo-synthons in Sonogashira cross-coupling reactions and allows the synthesis of very soluble complexes. (C) 2002 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(02)01559-9
• 作为产物：
  描述：

  1,6-二溴芘 、 4'-ethynyl-2,2':6',6-terpyridine 在 四(三苯基膦)钯 、 二异丙胺 作用下， 以 甲苯 为溶剂， 以75%的产率得到4'-(6-Bromo-pyren-1-ylethynyl)-[2,2';6',2'']terpyridine
  参考文献：
  名称：

  Stepwise construction of pyrene bridged polytopic ligands carrying acetylenic tethers

  摘要：

  Reliable and practical synthetic routes for the construction of. polytopic bipyridine or terpyridine frameworks are presented. These ligands are prepared by sequential Pd-promoted cross-coupling reactions between selected ethynyl substituted bipyridine or terpyridine building blocks and 1,6-dibromopyrene. A convergent synthetic route for the preparation of Ru complexes bearing peripheral uncomplexed fragments has been established starting from preorganized building blocks carrying a bromide function. This protocol highlights the use of metallo-synthons in Sonogashira cross-coupling reactions and allows the synthesis of very soluble complexes. (C) 2002 Published by Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(02)01559-9