7β,17α-Dihydroxy-1,4-pregnadiene-3,20-dione | 79172-22-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 7β,17α-Dihydroxy-1,4-pregnadiene-3,20-dione
• 英文别名: (7S,8R,9S,10R,13S,14S,17R)-17-acetyl-7,17-dihydroxy-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
• CAS: 79172-22-8
• 化学式: C₂₁H₂₈O₄
• 分子量: 344.451
• InChiKey: TVWCJDSKJSLPNT-UJPCIWJBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  6β,7β-Oxy-17α-hydroxy-1,4-pregnadiene-3,20-dione 在 Me₃N-HCl buffer 作用下， 以 甲醇 、 水 为溶剂， 以36%的产率得到7β,17α-Dihydroxy-1,4-pregnadiene-3,20-dione
  参考文献：
  名称：

  Electrochemical reduction of epoxy ketones

  摘要：

  DOI：

  10.1021/jo00337a044

文献信息

• Use of hydroxyprogesterone derivatives for enhancing health and physical performance
  申请人：Marchewitz Eric D.

  公开号：US20120277201A1

  公开（公告）日：2012-11-01

  A method for the use of derivatives of hydroxyprogesterone (17-alpha-hydroxypregn-4-ene-3,20-dione) to enhance health and physical performance in humans and more particularly to the use of hydroxyprogesterone derivatives for restoring renal hormonal balance, decreasing body weight, reducing adipose tissue, increasing endurance, promoting skeletal muscle growth, boosting androgen levels, inhibiting aromatase, and increasing cognitive function.
• Use of Hydroxyprogesterone Derivatives for Enhanced Health and Physical Performance II
  申请人：Marchewitz Eric

  公开号：US20190038637A1

  公开（公告）日：2019-02-07

  A method for the use of derivatives of hydroxyprogesterone (17-alpha-hydroxypregn-4-ene-3,20-dione) to enhance health and physical performance in humans and more particularly to the use of hydroxyprogesterone derivatives for restoring renal hormonal balance, decreasing body weight, reducing adipose tissue, increasing endurance, promoting skeletal muscle growth, boosting androgen levels, inhibiting aromatase, and increasing cognitive function.
• US4124707A
  申请人：——

  公开号：US4124707A

  公开（公告）日：1978-11-07